Self-Reported Prevalence of Gluten-Related Disorders and Adherence to Gluten-Free Diet in Colombian Adult Population
Self-Reported Prevalence of Gluten-Related Disorders and Adherence to Gluten-Free Diet in Colombian Adult Population
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DOI：
10.1155/2016/4704309
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发表时间：
2016-01-01
影响因子：
2
通讯作者：
Ontiveros, Noe
中科院分区：
文献类型：
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作者：
Cabrera-Chavez, Francisco;Maria Granda-Restrepo, Diana;Ontiveros, Noe
背景乳糜泻似乎是罕见的，但目前还没有数据的患病率有症状的不良反应，面筋或坚持无麸质饮食（GFD）在这一人群。瞄准！评估哥伦比亚人群中自我报告的麸质不良反应、GFD依从性和麸质相关疾病的患病率。方法.在哥伦比亚西北部的一个人群中进行了一项基于自我管理的横断面研究。结果小麦/麸质不良反应和复发不良反应的估计患病率分别为（95%CI）7.9%（6.5-9.6）和5.3%（4.1-6.7），坚持GFD 5.9%（4.7-7.4），小麦过敏0.74%（0.3-1.4）和非腹腔麸质敏感4.5%（3.5-5.8）。没有自我报告的乳糜泻病例。自我报告的医生诊断的面筋相关疾病的患病率为0.41%（0.17-0.96）。大多数受访者报告坚持GFD，而没有医生诊断的谷蛋白相关疾病（97.2%）。面筋回避者的比例为17.2%（15.2-19.5）。大多数患者未报告对小麦/面筋的反复不良反应（87.0%）。结论.在哥伦比亚很少正式诊断出非乳糜泻麸质敏感性，但这一人群迄今为止报告的坚持GFD的患病率最高。因此，大多数受访者避免小麦和/或面筋为基础的产品的原因以外的健康相关的症状。
Background. Celiac disease seems to be rare in Colombians, but there are currently no data about the prevalence rates of symptomatic adverse reactions to gluten or adherence to gluten-free diet (GFD) in this population. Aim. to evaluate the self-reported prevalence rates of adverse reactions to gluten, adherence to GFD, and gluten-related disorders at population level in Colombia. Methods. A self-administered questionnaire-based cross-sectional study was conducted in a population from Northwest Colombia. Results. The estimated prevalence rates were (95% CI) 7.9% (6.5-9.6) and 5.3% (4.1-6.7) for adverse and recurrent adverse reactions to wheat/gluten, respectively, adherence to GFD 5.9% (4.7-7.4), wheat allergy 0.74% (0.3-1.4), and nonceliac gluten sensitivity 4.5% (3.5-5.8). There were no self-reported cases of celiac disease. Prevalence of self-reported physician-diagnosis of gluten-related disorders was 0.41% (0.17-0.96). Most respondents reported adherence to GFD without a physician-diagnosis of gluten-related disorders (97.2%). The proportion of gluten avoiders was 17.2% (15.2-19.5). Most of them did not report recurrent adverse reactions to wheat/gluten (87.0%). Conclusions. Nonceliac gluten sensitivity is rarely formally diagnosed in Colombia, but this population has the highest prevalence rate of adherence to GFD reported to date. Consequently, most respondents were avoiding wheat- and/or gluten-based products for reasons other than health-related symptoms.