The clinical heterogeneity of entirely nonenhancing CNS lymphoma: a case series.
The clinical heterogeneity of entirely nonenhancing CNS lymphoma: a case series.
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DOI：
10.2217/cns-2020-0020
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发表时间：
2021-03-01
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影响因子：
--
通讯作者：
Ambady P
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文献类型：
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作者：
Bowden SG;Munger DN;Thiessen J;Woll SCS;Han SJ;Neuwelt EA;Barajas RF;Ambady P
中枢神经系统淋巴瘤通常呈现非典型影像学特征，导致诊断和开始治疗的延迟。其中最罕见报道的是完全不增强的中枢神经系统淋巴瘤，估计其发病率约为 1%。在这里，我们介绍了三例免疫功能正常患者的初发和复发时的非增强中枢神经系统淋巴瘤病例，以及原发性和继发性中枢神经系统淋巴瘤。发现弥散加权成像和灌注加权成像在某些情况下有助于诊断。
CNS lymphoma often presents with atypical imaging characteristics leading to delay in diagnosis and initiation of treatment. Among the most rarely reported of these is entirely nonenhancing CNS lymphoma, which is estimated at an incidence of about 1%. Here, we present three cases of nonenhancing CNS lymphoma in immune competent patients at both initial presentation and recurrence and in primary as well as secondary CNS lymphoma. Diffusion- and perfusion-weighted imaging was found helpful in diagnosis in some cases.