Orthostatic intolerance: A disorder of young women
Orthostatic intolerance: A disorder of young women
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DOI：
10.1097/00006254-200004000-00025
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发表时间：
2000-04-01
影响因子：
6.2
通讯作者：
Robertson, D
中科院分区：
文献类型：
--
作者：
Ali, YS;Daamen, N;Robertson, D
立位不耐受（OI）是妇科医生发现的其他健康女性的重要残疾原因。直立性心动过速通常是在OI患者中发现的最明显的血流动力学异常，但症状可能包括头晕、视觉变化、头部或颈部不适、注意力不集中、疲劳、心悸、颤抖、焦虑，以及在某些情况下昏厥（晕厥）。它是原发性高血压之后最常见的血压调节障碍，传统上OI患者为育龄妇女。据估计，至少有500，000美国人患有某种形式的OI，这些患者构成了最大的群体，被转介到专门研究植物神经紊乱的中心。本文综述了近年来对这一疾病的认识、导致立位不耐受的潜在病理生理机制以及目前可用于治疗这类患者的替代治疗方法。目标受众：妇产科医生、家庭医生学习目标：读完这篇文章后，读者将能够描述与特发性立位不耐受相关的常见体征和症状，识别与特发性立位不耐受有相似表现的各种疾病，并描述潜在的治疗方案。
Orthostatic intolerance (OI) is a cause of significant disability in otherwise healthy women seen by gynecologists. Orthostatic tachycardia is often the most obvious hemodynamic abnormality found in OI patients, but symptoms may include dizziness, visual changes, discomfort in the head or neck, poor concentration, fatigue, palpitations, tremulousness, anxiety, and, in some cases, fainting (syncope). It is the most common disorder of blood pressure regulation after essential hypertension, and patients with OI are traditionally women of childbearing age. Estimates suggest that at least 500,000 Americans suffer from some form of OI, and such patients comprise the largest group referred to centers specialized in autonomic disorders. This article reviews recent advances made in the understanding of this condition, potential pathophysiological mechanisms contributing to orthostatic intolerance, and therapeutic alternatives currently available for the management of these patients.Target Audience: Obstetricians & Gynecologists, Family PhysiciansLearning Objectives: After completion of this article, the reader will be able to describe the common signs and symptoms associated with idiopathic orthostatic intolerance, to identify the various conditions that have similar presentations as idiopathic orthostatic intolerance and to describe potential treatment options.