The retrotrapezoid nucleus as a central brainstem area for central and peripheral chemoreceptor interactions

The retrotrapezoid nucleus as a central brainstem area for central and peripheral chemoreceptor interactions
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后梯形核作为中枢脑干区域,用于中枢和外周化学感受器相互作用

DOI:
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发表时间:
2016
影响因子:
2.7
通讯作者:
T. Moreira
T. Moreira
中科院分区:
医学4区
文献类型:
--
作者:
A. Takakura;T. Moreira

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一段时间以来,已知中枢呼吸化学感受器参与调节组织CO2/H+的变化,并向呼吸中枢发送兴奋性驱动,以直接调节呼吸的深度和频率(参见Guyenet,2014)。此外,位于颈动脉体中的外周化学传感器已经被认为是感测O2和CO2/H+的动脉水平,并将该信息传递到心肺中枢以调节呼吸和交感神经流出,从而确保充分的通气-灌注
It has been known for some time that central respiratory chemoreceptors are involved in the regulation of changes in tissue CO2/H+ and send excitatory drive to respiratory centres to regulate depth and frequency of breathing directly (see Guyenet, 2014). In addition, peripheral chemosensors located in the carotid bodies have been recognized as sensing arterial levels of O2 and CO2/H+ and communicating this information to cardiorespiratory centres to regulate breathing and sympathetic outflow to ensure adequate ventilation–perfusion
DOI: 10.1002/cphy.c140004
发表时间: 2014-10
影响因子: 5.8
作者:
Guyenet PG
通讯作者: Guyenet PG