ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY AN ADVANCED ANALYTICAL TOOL
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY AN ADVANCED ANALYTICAL TOOL
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发表时间：
2014
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通讯作者：
Pooja Sangale;Dr. Charushila Bhangale
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作者：
Pooja Sangale;Dr. Charushila Bhangale
超高效液相色谱 (UPLC) 利用颗粒化学性能、系统优化、检测器设计以及数据处理和控制方面取得的技术进步。与 HPLC 相比，使用低于 2 mm 的颗粒和更高线速度的流动相以及在更高压力下运行的仪器，可以显着提高分辨率、灵敏度和分析速度。这种新的分析分离科学类别保留了 HPLC 的实用性和原理，同时在色谱性能方面实现了阶跃功能改进。本综述介绍了 UPLC 的理论并总结了该领域的一些最新工作
Ultra Performance Liquid Chromatography (UPLC) takes the advantage of technological strides made in particle chemistry performance, system optimization, detector design and data processing and control. Using sub 2 mm particles and mobile phases at higher linear velocities and instrumentation that operates at higher pressures than those used in HPLC, dramatic increases in resolution, sensitivity and speed of analysis can be obtained. This new category of analytical separation science retains the practicality and principles of HPLC while creating a step function improvement in chromatographic performance. This review introduces the theory of UPLC and summarizes some of the most recent work in the field