Effectiveness of a Web-Based Cognitive Behavioural Intervention for Subthreshold Depression: Pragmatic Randomised Controlled Trial
Effectiveness of a Web-Based Cognitive Behavioural Intervention for Subthreshold Depression: Pragmatic Randomised Controlled Trial
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DOI：
10.1159/000438673
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发表时间：
2015-01-01
影响因子：
22.8
通讯作者：
Berking, Matthias
中科院分区：
文献类型：
--
作者：
Buntrock, Claudia;Ebert, David;Berking, Matthias
背景：阈下抑郁症（sD）治疗的有效性研究仍然很少。该研究的目的是评估基于网络的引导自助干预（GET）的有效性。情绪增强剂）在治疗sD。研究方法：通过大型健康保险公司从普通人群中招募的sD参与者（n = 406）被随机分配到基于网络的认知行为干预或增强护理。主要结局是治疗后和6个月随访时用流行病学研究中心抑郁量表测量的抑郁症状严重程度的降低。结果如下：与对照组（d = 0.29; 95%CI：0.10-0.49）相比，干预组的参与者表现出显著更大的抑郁症状严重程度的前后降低（d = 1.06; 95%CI：0.86-1.27）。相应的组间效应量为d = 0.69（95% CI：0.49-0.89）。6个月随访时，该效应降至d = 0.28（95%CI：0.09-0.48），但仍具有统计学显著性（F-1，F-403 = 9.240，p = 0.003）。结论：本研究支持的想法，解决问题加上行为激活是一种有效的治疗sD。此外，在互联网上提供这种干预可能是一个有前途的战略，大规模传播的心理干预sD。(C)2015 S. Karger AG，巴塞尔
Background: Research on the effectiveness of treatments for subthreshold depression (sD) is still scarce. The aim of the study was to evaluate the efficacy of a web-based guided self-help intervention (GET. ON Mood Enhancer) in the treatment of sD. Methods: Participants with sD (n = 406) recruited from the general population via a large health insurance company were randomly allocated to a web-based cognitive behavioural intervention or to enhanced care-as-usual. The primary outcome was the reduction in depressive symptom severity as measured with the Center for Epidemiological Studies Depression Scale at post-treatment and at 6-month follow-up. Results: Participants in the intervention group showed a significantly greater pre-post reduction in depressive symptom severity (d = 1.06; 95% CI: 0.86-1.27) compared to the control condition (d = 0.29; 95% CI: 0.10-0.49). The corresponding between-group effect size was d = 0.69 (95% CI: 0.49-0.89). At 6-month follow-up the effect was reduced to d = 0.28 (95% CI: 0.09-0.48) but was still statistically significant (F-1,F-403 = 9.240, p = 0.003). Conclusions: This study lends support to the idea that problem solving coupled with behavioural activation is an effective treatment for sD. In addition, the delivery of this intervention over the Internet might be a promising strategy for the dissemination of psychological interventions for sD on a large scale. (C) 2015 S. Karger AG, Basel