Nickel-Catalyzed Enantioselective C-C Bond Formation through Csp2-O Cleavage in Aryl Esters
Nickel-Catalyzed Enantioselective C-C Bond Formation through Csp2-O Cleavage in Aryl Esters
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DOI：
10.1002/anie.201412051
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发表时间：
2015-03-23
影响因子：
16.6
通讯作者：
Martin, Ruben
中科院分区：
文献类型：
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作者：
Cornella, Josep;Jackson, Evan P.;Martin, Ruben
我们报告了第一个通过C-O键裂解使用芳基酯对应物的对映选择性C-C键形成。该方法的特点是底物范围广，导致四元立体中心的形成，具有高产率和不对称诱导。
We report the first enantioselective C-C bond formation through C-O bond cleavage using aryl ester counterparts. This method is characterized by its wide substrate scope and results in the formation of quaternary stereogenic centers with high yields and asymmetric induction.