Cognitive function after pre-eclampsia: an explorative study
Cognitive function after pre-eclampsia: an explorative study
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DOI：
10.1080/01674820802546212
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发表时间：
2009-01-01
影响因子：
3.1
通讯作者：
van der Werf, Sieberen P.
中科院分区：
文献类型：
--
作者：
Baecke, Martina;Spaanderman, Mark E. A.;van der Werf, Sieberen P.
背景。先兆子痫和子痫与脑损伤有关。在这些与妊娠相关的血管并发症之后，经常报告出现记忆力和注意力问题。我们测试了这样的假设：与健康的经产对照相比，先前患有先兆子痫的女性认知功能受损。方法。最近有早产先兆子痫 (PPE; n=47)、足月先兆子痫 (TPE; N=18)、早产 (PBI; n=32) 或妊娠平安 (UPR; n=72) 病史的女性完成了一组调查问卷，测量认知问题、创伤后应激障碍 (PTSD)、抑郁、焦虑和疲劳。此外，我们还测试了 PPE 和 UPR 参与者的神经心理学表现。结果。 PBI 与较高水平的创伤后痛苦症状有关，这反过来又降低了 PPE 女性的神经心理学测试表现。尽管如此，PPE 和 TPE 组的女性并没有比 PBI 和 UPR 组的女性报告更多的认知问题，但 PPE 提出了心理社会护理的需求。结论。认知问题在年轻母亲中很常见。经过测试，只有那些患有心理共病的人才会出现神经心理障碍。
Background. Pre-eclampsia and eclampsia relate to cerebral damage. Memory and concentration problems are frequently reported after these pregnancy-related vascular complications. We tested the hypothesis that in formerly pre-eclamptic women cognitive functioning is impaired as compared with healthy parous controls. Methods. Women with a recent history of pre-term pre-eclampsia (PPE; n=47), term pre-eclampsia (TPE; N=18), pre-term birth (PBI; n=32) or an uneventful pregnancy (UPR; n=72) completed a set of questionnaires, measuring cognitive problems, PTSD, depression, anxiety and fatigue. In addition, in PPE and UPR participants we tested neuropsychological performance. Results. PBI is related to higher levels of post-traumatic distress symptoms, which in turn diminished the neuropsychological test performance of PPE women. Nonetheless, women in the PPE and TPE groups did not report more cognitive problems than women in the PBI and UPR groups, but PPE raised the need for psychosocial cared. Conclusions. Cognitive complaints are common amongst young mothers. When tested, only those with psychological co-morbidity have neuropsychological impairment.