Leptin predicts a decline in moderate to vigorous physical activity in minority female children at risk for obesity.
Leptin predicts a decline in moderate to vigorous physical activity in minority female children at risk for obesity.
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DOI：
10.1111/j.2047-6310.2012.00091.x
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发表时间：
2013-02
影响因子：
3.8
通讯作者：
Spuijt-Metz D
中科院分区：
文献类型：
--
作者：
Belcher BR;Chou CP;Nguyen-Rodriguez ST;Hsu YW;Byrd-Williams CE;McClain AD;Weigensberg MJ;Spuijt-Metz D
瘦素可能会影响青春期开始时的中度至剧烈体力活动 (MVPA)。这种关联的方向和程度尚不清楚。旨在确定基线瘦素对肥胖高危少数民族女孩一年内 MVPA 的影响。数据来自 TRANSITIONS，这是一项针对与年龄相关的 MVPA 下降的纵向观察研究。 50 名基线年龄为 8-11 岁的青春期女孩参与了研究。使用双抗体放射免疫测定通过重复测定收集基线瘦素 (ng/mL)。 MVPA（分钟/天）是使用加速度计测量至少四个 10 小时的天，每季度测量一次，持续时间长达一年。持续瘦素与 MVPA 呈负相关 (p=0.001)，与基线时的中心性肥胖无关，并预测 MVPA 在一年内下降 (p=0.002)。出于描述目的，基线瘦素在样本中位数处被分为“高瘦素”和“低瘦素”类别，以确定这些组之间的 MVPA 轨迹是否存在差异。与“瘦素高”的女孩相比，基线时“瘦素低”的女孩在基线、第 1 次访视和第 2 次访视时的 MPVA 水平显着更高。高瘦素水平预示 MVPA 在一年内会下降近 12.6%。这些发现为女孩进入青春期时 MVPA 下降的生物学基础提供了支持。
Leptin may influence moderate to vigorous physical activity (MVPA) at the start of puberty. The direction and magnitude of this association is unclear. To determine the effect of baseline leptin on MVPA over one year in minority girls at high-risk for obesity. Data came from TRANSITIONS, a longitudinal observational study on the age-related MVPA decline. Fifty peri-pubertal girls aged 8–11 years at baseline participated. Baseline leptin (ng/mL) was collected via a duplicated assay using a double antibody Radio Immune Assay. MVPA (min/day) was measured using accelerometers for at least four 10-hr days on a quarterly basis for up to one year. Continuous leptin was negatively related to MVPA (p=0.001) independent of central adiposity at baseline and predicted the MVPA decline over one year (p=0.002). For descriptive purposes, baseline leptin was dichotomized at the sample median into ‘high leptin’ and ‘low leptin’ categories to determine whether MVPA trajectories differed between these groups. Girls with ‘low leptin’ at baseline had significantly higher levels of MPVA at baseline, visit 1, and visit 2 compared to girls with ‘high leptin’. High leptin levels predicted nearly a 12.6% decline in MVPA over one year. These findings provide support for the biological basis of declining MVPA as girls enter puberty.
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影响因子：
7.6
作者：
Pate, Russell R.;Stevens, June;Webber, Larry S.;Dowda, Marsha;Murray, David M.;Young, Deborah R.;Going, Scott
通讯作者：
Going, Scott
影响因子：
5.8
作者：
Heptulla, R;Smitten, A;Caprio, S
通讯作者：
Caprio, S
影响因子：
3.4
作者：
Evenson, Kelly R.;Catellier, Diane J.;McMurray, Robert G.
通讯作者：
McMurray, Robert G.
影响因子：
158.5
作者：
Kimm, SYS;Glynn, NW;Liu, K
通讯作者：
Liu, K
DOI：
10.1249/01.mss.0000093612.59984.0e
发表时间：
2003-11-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
McMurray, RG;Harrell, JS;Hu, JH
通讯作者：
Hu, JH