The Role of Allergy and Smoking in Chronic Rhinosinusitis and Polyposis
The Role of Allergy and Smoking in Chronic Rhinosinusitis and Polyposis
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DOI：
10.1097/mlg.0b013e31817d01b8
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发表时间：
2008-09-01
期刊：
影响因子：
2.6
通讯作者：
Keen, Kevin J.
中科院分区：
文献类型：
--
作者：
Houser, Steven M.;Keen, Kevin J.
目标/假设：本文考虑了过敏性鼻炎和慢性鼻窦炎 (CRS) 的相互关系。探讨了常年过敏和吸烟对鼻窦手术患者息肉病的负面影响。研究设计：第一作者对因慢性鼻窦炎而接受功能性内窥镜鼻窦手术的患者进行了为期 6 年的回顾性图表审查。方法：通过汇总统计数据和多重线性逻辑模型来仔细检查受试者的过敏状况和吸烟史，以预测是否存在息肉病。 结果：受试者人群中常年性过敏性鼻炎 (PAR) 的患病率很高 (56.4%)。 PAR 和吸烟均与鼻息肉病相关（分别为 P = .0073 和 P = .0114）。结论：PAR 和 CRS 的密切关联表明可能存在因果关系。过敏性鼻炎的治疗和戒烟可以更好地控制慢性增生性鼻窦炎。
Objectives/Hypothesis: The article considers the interrelatedness of allergic rhinitis and chronic rhinosinusitis (CRS). The negative impact of perennial allergy and tobacco use on polyposis in sinus surgery patients is explored.Study Design: A retrospective chart review, performed by the first author over a 6-year period, of patients who underwent functional endoscopic sinus surgery for CRS.Methods: The subjects' allergy status and smoking history are scrutinized by summary statistics and a multiple linear logistic model for predicting the presence of polyps.Results: High prevalence of perennial allergic rhinitis (PAR) is seen in the subject population (56.4%). Both PAR and tobacco use are associated with nasal polyposis (P = .0073 and P = .0114, respectively).Conclusions: The close association of PAR and CRS suggests a possible causal link. Management of allergic rhinitis and tobacco cessation may provide greater control of chronic hyperplastic rhinosinusitis.