Short Report: Attribution of Malnutrition to Cause-Specific Diarrheal Illness: Evidence from a Prospective Study of Preschool Children in Mirpur, Dhaka, Bangladesh
Short Report: Attribution of Malnutrition to Cause-Specific Diarrheal Illness: Evidence from a Prospective Study of Preschool Children in Mirpur, Dhaka, Bangladesh
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DOI：
10.4269/ajtmh.2009.80.824
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发表时间：
2009-05-01
影响因子：
3.3
通讯作者：
Petri, William A., Jr.
中科院分区：
文献类型：
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作者：
Mondal, Dinesh;Haque, Rashidul;Petri, William A., Jr.
我们检查了营养不良（体重不足 [WAZ] < -2）是否会同等地增加所有肠道病原体的腹泻风险。这项研究于 1999 年 1 月至 2002 年 7 月期间在达卡城市贫民窟米尔普尔进行了前瞻性研究。该研究纳入了 289 名 2-5 岁的孟加拉国儿童（147 名男性和 142 名女性）。入学时，39% 的儿童存在营养不良。医护人员每隔一天都会拜访并采访父母和孩子，以了解有关腹泻发作的详细信息。从 62% 的腹泻发作中成功采集了粪便样本。在已确定的肠道病原体中，只有产肠毒素大肠杆菌 (ETEC)、隐孢子虫和溶组织内阿米巴在营养不良儿童中更为常见。我们的结论是，与腹泻疾病相关的肠道病原体的营养不良风险并不相同。
We examined whether malnutrition (underweight [WAZ] < -2) increased the risk of diarrhea equally for all enteropathogens. The study was conducted prospectively between January 1999 and July 2002 in Mirpur, an urban slum in Dhaka. Two hundred eighty-nine Bangladeshi children (147 male and 142 female) 2-5 years of age were included in the study. Malnutrition was present in 39% of the children at the time of enrollment. The parents and children were visited and interviewed every other day by health care workers for details about any diarrheal episodes. Stool samples were successfully collected from 62% of episodes of diarrhea. Of the identified enteropathogens, only enterotoxigenic Escherichia coli (ETEC), Cryptosporidium sp., and Entamoeba histolytica were significantly more prevalent in malnourished children. We concluded that the malnutrition attributed risk is not equal for enteric pathogens associated with diarrheal illness.