The Role of Diet and Supplements in Vitiligo Management
The Role of Diet and Supplements in Vitiligo Management
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DOI：
10.1016/j.det.2016.11.012
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发表时间：
2017-04-01
影响因子：
2.4
通讯作者：
Nashawati, Rama
中科院分区：
文献类型：
--
作者：
Grimes, Pearl E.;Nashawati, Rama
白癜风是一种自身免疫性疾病，涉及氧化应激和免疫系统之间的相互作用。初步观察表明，饮食中面筋的存在可能在一些患者的白癜风发展中发挥作用，但到目前为止，针对白癜风的饮食尚未进行研究。口服补充剂的作用，包括维生素、矿物质和植物药，由于其抗氧化和免疫调节活性，越来越多地作为常规医疗的辅助手段而被研究。研究表明，这些药物中的许多作为单一疗法可能有一定的疗效，但更多的时候是作为局部药物和光疗的辅助药物。
Vitiligo is an autoimmune disorder that involves the interplay between oxidative stress and the immune system. Preliminary observations suggest that the presence of gluten in the diet may play a role in vitiligo development in some patients, but to date vitiligo-specific diets have not been studied. The role of oral supplements, including vitamins, minerals, and botanicals, is increasingly being investigated as adjuncts to conventional medical treatment due to their antioxidant and immunomodulatory activity. Studies suggest that many of these agents may have some efficacy as monotherapy, but more often as adjuncts to topical agents and phototherapy.