Selective Base-Catalyzed Isomerization of Glucose to Fructose
Selective Base-Catalyzed Isomerization of Glucose to Fructose
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DOI：
10.1021/cs501197w
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发表时间：
2014-12-01
期刊：
影响因子：
12.9
通讯作者：
Tessonnier, Jean-Philippe
中科院分区：
文献类型：
--
作者：
Liu, Chi;Carraher, Jack M.;Tessonnier, Jean-Philippe
果糖是纤维素生物质转化为生物燃料和可再生平台化学品的关键中间体。生物质衍生的葡萄糖可以用Lewis酸或Bronsted碱催化剂异构化为果糖。路易斯酸通常是首选的，因为碱性条件会促进大量的副反应。人们普遍认为，只有使用无机碱才能实现低于10%的低果糖产量。在这里，果糖以32%的产率合成使用市售有机胺。葡萄糖转化和果糖选择性与路易斯酸相当，这为碱基催化途径开辟了新的视角。
Fructose is a key intermediate in the conversion of cellulosic biomass to biofuels and renewable platform chemicals. Biomass-derived glucose can be isomerized to fructose using either Lewis acid or Bronsted base catalysts. Lewis acids are typically preferred as alkaline conditions promote a large number of side reactions. It is widely admitted that only low fructose yields, below 10%, are achievable with inorganic bases. Here, fructose was synthesized with 32% yield using commercially available organic amines. Glucose conversion and fructose selectivity were comparable to Lewis acids, which opens new perspectives for the base-catalyzed pathway.