Behavioral assessment of visual acuity in mice and rats
Behavioral assessment of visual acuity in mice and rats
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DOI：
10.1016/s0042-6989(00)00081-x
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发表时间：
2000-01-01
期刊：
影响因子：
1.8
通讯作者：
Douglas, RM
中科院分区：
文献类型：
--
作者：
Prusky, GT;West, PWR;Douglas, RM
我们开发了一种简单的基于计算机的辨别任务，可以快速确定啮齿类动物的视力。在装有浅水的梯形水箱宽端的两个监视器之一上随机显示光栅。动物被训练游向屏幕，并在固定距离处选择显示格栅的屏幕并逃到隐藏在其下方的水下平台。小鼠和大鼠都能很快学会这项任务。当大多数 C57BU6 小鼠的空间频率增加超过 0.5 个周期时，性能下降到 70% 以下，而 Long-Evans 大鼠的空间频率增加到每度 (cpd) 约 1.0 个周期时，性能会下降到 70% 以下。 (C) 2000 Elsevier Science Ltd. 保留所有权利。
We have developed a simple computer-based discrimination task that enables the quick determination of visual acuities in rodents. A grating is displayed randomly on one of two monitors at the wide end of a trapezoidal-shaped tank containing shallow water. Animals are trained to swim toward the screens, and at a fixed distance, choose the screen displaying the grating and escape to a submerged platform hidden below it. Both mice and rats learn the task quickly. Performance falls below 70% when the spatial frequency is increased beyond 0.5 cycles in most C57BU6 mice, and around 1.0 cycles per degree (cpd) in Long-Evans rats. (C) 2000 Elsevier Science Ltd. Ail rights reserved.