Synthesis and optical properties of water soluble CdSe/CdS quantum dots for biological applications
Synthesis and optical properties of water soluble CdSe/CdS quantum dots for biological applications
复制标题
DOI：
10.1088/2043-6262/3/2/025017
复制
发表时间：
2012-05
影响因子：
--
通讯作者：
V. Chu;T. H. Lien Nghiem;T. Le;Dinh Lam Vu;Hong Nhung Tran;Thi Kim Lien Vu
中科院分区：
文献类型：
--
作者：
V. Chu;T. H. Lien Nghiem;T. Le;Dinh Lam Vu;Hong Nhung Tran;Thi Kim Lien Vu
以柠檬酸钠为表面活性剂，在水溶液中直接合成了水溶性的CdSe/CdS量子点。量子点在水中单分散，在紫外光激发下具有较强的发光强度。通过改变合成条件，量子点的最大发射波长可以在555~615 nm的较宽范围内调节。合成了水溶性的CdSe和CdSe/CDS量子点，结果表明制备的量子点质量较高，具有较窄的发光带和光稳定性。结果表明，在pH值为8-8.5的生理环境中，光致发光强度最强。当量子点表面包覆一层聚乙二醇层或牛血清白蛋白层时，发光强度增加，寿命也增加。
Water soluble CdSe/CdS quantum dots (QDs) have been synthesized directly in aqueous solution with sodium citrate as surfactant agent. The QDs are mono-dispersed in water and have strong luminescent emission intensity under excitation of ultraviolet light. The emission maxima of the QDs can be tuned in a wider range from 555 to 615 nm in water by changing synthesis conditions. The result of the synthesis of water-soluble CdSe and CdSe/CdS QDs shows the high quality of the QDs with the quite narrow luminescence emission band and photostability. The results show the strongest intensity of photoluminescence emission in media with pH value at about from 8–8.5, which are pH physiological environments. The luminescence intensity increases when the QDs are coated with a polyethylene glycol (PEG) or bovine serum albumin (BSA) protein layer, the lifetime also increases.