Influence of Smoking History on Imaging Characteristics Among Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: A Blinded Matched-Pair Analysis
Influence of Smoking History on Imaging Characteristics Among Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: A Blinded Matched-Pair Analysis
复制标题
DOI：
10.1097/rct.0000000000000100
复制
发表时间：
2014-09-01
影响因子：
1.3
通讯作者：
Ginsberg, Lawrence E.
中科院分区：
文献类型：
--
作者：
Cantrell, Sarah C.;Reid, Holly H.;Ginsberg, Lawrence E.
Background and Purpose: Human papillomavirus (HPV)-positive oropharyngeal cancers represent a distinct clinical entity with more favorable prognosis than do HPV-negative oropharyngeal cancers. However, among patients with HPV-positive oropharyngeal carcinomas, those with a significant smoking history have a much worse prognosis. Recently, imaging characteristics of oropharyngeal cancers were identified as markers of poor prognosis. The purpose of this study was to determine whether nodal imaging characteristics differ between smokers and never/light smokers with HPV-positive oropharyngeal cancer.Materials and Methods: A review of 130 pretreatment computed tomographic examinations of HPV-positive oropharyngeal cancers in smokers (>10 pack-years) and never/light smokers (
