DORSAL AND VENTRAL HIPPOCAMPAL LESIONS AND BEHAVIOR
DORSAL AND VENTRAL HIPPOCAMPAL LESIONS AND BEHAVIOR
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DOI：
10.1016/0031-9384(68)90174-1
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发表时间：
1968-01-01
影响因子：
2.9
通讯作者：
NADEL, L
中科院分区：
文献类型：
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作者：
NADEL, L
在一系列测试中，将背侧或腹侧海马损伤的大鼠的行为与对照组的行为进行比较。背侧海马损伤使大鼠在新的情况下过度活跃，不影响习惯化率，促进收购的条件性情绪反应（CER），并推迟收购的单向主动回避反应。海马损伤使大鼠在新的情况下过度活跃，影响探索性反应的习惯化率，延缓CER的消退，并倾向于促进单向主动回避反应的获得。这些结果表明，背侧和腹侧海马在功能上是不同的。当应用到以前的数据检查，这种区别可能有助于澄清目前的混乱海马功能。背侧和腹侧区的可能功能进行了讨论。
The behavior of rats with either dorsal or ventral hippocampal lesions was compared to that of a control group in a series of tests. Dorsal hippocampal lesions made rats hyperactive in novel situations, did not affect rates of habituation, facilitated acquisition of a conditioned emotional response (CER), and retarded acquisition of a one-way active avoidance response. Ventral hippocampal lesions made rats hyperactive in novel situations, affected the rate of habituation of exploratory responses, retarded extinction of the CER, and tended to facilitate acquisition of the one-way active avoidance response. These results demonstrate that the dorsal and ventral hippocampus are functionally distinct. When applied to an examination of previous data, this differentiation may help to clarify present confusion about hippocampal function. Possible functions of the dorsal and ventral areas are discussed.