Equity in global health research in the new millennium: trends in first-authorship for randomized controlled trials among low-and middle-income country researchers 1990-2013
Equity in global health research in the new millennium: trends in first-authorship for randomized controlled trials among low-and middle-income country researchers 1990-2013
复制标题
DOI：
10.1093/ije/dyw313
复制
发表时间：
2016-12-01
影响因子：
7.7
通讯作者：
Rahadi, Arie
中科院分区：
文献类型：
--
作者：
Kelaher, Margaret;Ng, Lye;Rahadi, Arie
背景资料：发展低收入和中等收入国家的研究能力已被证明是国际卫生方案和卫生研究能够在这些国家创造持续利益的关键途径之一。方法：对1990 - 2013年在LMIC开展的艾滋病、疟疾和结核病随机对照试验（RCT）的研究文献进行系统回顾，并对作者所属机构进行分析。从文章中提取的关键变量包括作者关系、资金来源、疾病、干预类型、地区和出版年份。Poisson回归被用来探索这些关键变量对LMIC第一作者随着时间的推移的影响。结果：共确定了1593篇文章，其中49.8%的LMIC第一作者。从1990年至2000年，共公布了222项试验，从2001年至2013年，共公布了1371项试验，在此期间逐年稳步增加，在非洲进行的试验尤其明显。虽然LMIC第一作者的绝对总数有所增加，但作为所有作者的比例，它下降了。2000年后，非LMIC第一作者的相对增长率为11.8倍，LMIC作者为2.8倍。LMIC的第一作者随着时间的推移增加了研究资助的LMIC，但LMIC的第一作者随着时间的推移下降了研究资助的高收入国家（HIC）。结论：在艾滋病毒/艾滋病，疟疾和结核病在非洲的试验数量的绝对增加导致了一个温和的增加LMIC的第一作者，和一个更大的增加非LMIC作者。研究结果表明，国际资助者采取更具包容性的政策对于将研究控制权转移到中低收入国家和改善未来的研究公平性非常重要。
Background: Developing the research capacity of low-and middle-income countries (LMICs) has been shown to be one of the key ways that international health programmes and health research can create sustained benefit in these countries. The aim of this study was to examine trends in first-authorship for researchers from LMIC institutions (LMIC first-authors) over the period 1990-2013.Methods: This study systematically reviewed research articles about randomized controlled trials (RCTs) in HIV/ AIDS, malaria and tuberculosis (TB) conducted in LMICs from 1990 to 2013, and identified the institutional affiliations of the authors. Key variables extracted from the articles included author affiliation, funding source, disease, intervention type, region and year of publication. Poisson regression was used to explore the impact of these key variables on LMIC first-authorship over time.Results: A total of 1593 articles were identified, of which 49.8% had LMIC first-authors. From 1990 to 2000 a total of 222 trials were published, and from 2001 to 2013 a total of 1371 trials were published, with a steady year-on-year increase over the period particularly evident in trials conducted in Africa. Whereas the absolute total number of LMIC first-authors has increased, as a proportion of all authors it declined. The relative rate increase in first-authorships post 2000 was 11.8-fold for non-LMIC first-authors and 2.8fold for LMIC authors. LMIC first-authorship increased over time for research funded from LMIC; but LMIC first-authorship declined over time for research funded from high income countries (HIC).Conclusions: The absolute increase in the number of trials in HIV/ AIDS, malaria and tuberculosis in Africa has led to a modest increase in LMIC first-authors, and a much larger increase in non-LMIC authors. The findings suggest that more inclusive policies by international funders are important in shifting research control to LMICs and improving research equity in the future.