Tumor recurrence after radiofrequency thermal ablation of hepatic tumors: Spectrum of findings on dual-phase contrast-enhanced CT

Tumor recurrence after radiofrequency thermal ablation of hepatic tumors: Spectrum of findings on dual-phase contrast-enhanced CT
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DOI:
10.2214/ajr.177.2.1770381
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发表时间:
2001-08-01
影响因子:
5
通讯作者:
Rhim, H
Rhim, H
中科院分区:
医学2区
文献类型:
--
作者:
Chopra, S;Dodd, GD;Rhim, H

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目的:探讨原发性和继发性肝脏恶性肿瘤射频消融术后肿瘤复发的CT征象。25名患者,10名肝细胞癌(HCC)和15名转移性肝癌患者,在射频消融后肿瘤复发,构成研究人群。结果肝内局部复发9例(90%),肝内局部复发11例(73%),远处肝内复发5例(50%),肝外复发7例(45%),肝外复发0例(0%),肝外复发6例(40%)。在12个肝内局部复发结节和24个转移灶中,8个(67%)和9个(38%)、4个(33%)和6个(38%)、0个和9个(37%)肝内局部复发分别为结节型、晕状型和肉眼膨大型,肝转移瘤中0个和9个(37%)。肝内局部复发表现为三种类型:结节状、晕状或肉眼增大。原发性和继发性肝肿瘤的复发部位和局部肝内肿瘤复发的形态模式不同。
OBJECTIVE, We conducted this study to determine the spectrum of CT findings of tumor recurrence after radiofrequency ablation of primary and secondary malignant hepatic tumors.MATERIALS AND METHODS. Twenty-five patients, 10 with hepatocellular carcinoma (HCC) and 15 patients with metastases who developed tumor recurrence after radiofrequency ablation of hepatic neoplasms, formed the study population. three observers reviewed the CT scans of these patients and evaluated the location (local intrahepatic, remote intrahepatic, or extrahepatic) of all recurrent lesions and the morphology and enhancement characteristics of local intrahepatic recurrences.RESULTS, Local intrahepatic recurrences were seen in nine patients (90%) and 11 patients (73%); remote intrahepatic recurrences, in five patients (50%) and seven patients (45%); and extrahepatic recurrences, in zero and six patients (40%) with recurrent HCC and recurrent metastases, respectively. Of the 12 nodules of local intrahepatic recurrences in HCC and the 24 in metastases, the patterns of local intrahepatic recurrences were of nodular, halo, and gross enlargement types in eight (67%) and nine (38%), four (33%) and six (38%), and zero and nine (37%) nodules in HCC and hepatic metastases, respectively, The number of local intrahepatic recurrent lesions enhancing in the arterial phase was significantly greater in HCC.CONCLUSION. Tumor recurrences occurred at intra- and extrahepatic sites after radiofrequency ablation of hepatic neoplasms. The local intrahepatic recurrences appeared in three patterns: nodular, halo, or gross enlargement. The sites of recurrence and the morphologic patterns of local intrahepatic tumor recurrence differed between primary and secondary hepatic neoplasms.