Thrombolytic Therapy of Acute Stroke

Thrombolytic Therapy of Acute Stroke
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DOI:
10.1161/circulationaha.111.060087
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发表时间:
2012-05-29
期刊:
影响因子:
37.8
通讯作者:
Feske, Steven K.
Feske, Steven K.
中科院分区:
医学1区
文献类型:
--
作者:
Feske, Steven K.

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2662或代表后勤和生物限制和挑战。1,2脑出血的相对易感性,3中风症状和体征的变异性使患者和临床医生都感到困惑,以及许多患者在中风症状发作后缺乏寻求医疗护理的紧迫性,这些因素也限制了急性中风与心肌梗死相比的治疗。因此,为了有效地实施脑卒中溶栓治疗,我们必须考虑和解决生物学和系统水平的障碍。
2662 itor represent logistical and biological limitations and challenges. 1, 2 The relative susceptibility of the brain to hemorrhage, 3 the variability of symptoms and signs of stroke that are confusing to both patients and clinicians, and the lack of urgency that many patients display in seeking medical care after the onset of stroke symptoms also limit therapy for acute stroke compared with myocardial infarction. Therefore, to implement thrombolytic therapies for stroke effectively, we must consider and address both biological and system-level obstacles.