Association between behavioral and psychological symptoms and psychotropic drug use among old people with cognitive impairment living in geriatric care settings
Association between behavioral and psychological symptoms and psychotropic drug use among old people with cognitive impairment living in geriatric care settings
复制标题
DOI：
10.1017/s1041610213000859
复制
发表时间：
2013-09-01
影响因子：
7
通讯作者：
Lovheim, Hugo
中科院分区：
文献类型：
--
作者：
Gustafsson, Maria;Sandman, Per-Olof;Lovheim, Hugo
背景：行为和心理症状在认知障碍个体中很常见，精神药物被广泛用于治疗。本研究的目的是描述老年护理机构中患有认知障碍的老年人使用精神药物和抗痴呆药物的患病率及其相关因素。方法：该研究包括住在瑞典韦斯特博滕县老年护理单位的2019名认知障碍患者。使用多维痴呆评估量表收集有关精神药物和抗痴呆药物使用、日常生活功能、认知功能以及行为和心理症状患病率的数据。结果：在研究人群中，1442人（71%）至少服用过一种精神药物（抗抑郁药（49%）、抗焦虑药、催眠药、镇静剂（36%）、抗精神病药（25%））。此外，363人（18%）接受了抗痴呆药物治疗。所有精神类药物和抗痴呆药物都发现了各种行为和心理症状之间的联系。言语破坏/注意力寻求行为与所有精神药物有关。抗精神病药物的使用与一些行为和心理症状有关，包括攻击行为。结论：本研究发现的行为和心理症状与精神药物使用之间的关联表明，尽管证据有限，但这些药物可用于治疗认知障碍个体的行为和心理症状。鉴于认知障碍老年人的不良反应风险很大，确保所使用的任何药物都是适当和安全的是很重要的。
Background: Behavioral and psychological symptoms are common among cognitively impaired individuals and psychotropic drugs are widely used for their treatment. The aim of this study was to describe the prevalence and associated factors of psychotropic and anti-dementia drug use among old people with cognitive impairment living in geriatric care settings.Methods: The study comprised 2,019 cognitively impaired people living in geriatric care units in the county of Vasterbotten, Sweden. Data concerning psychotropic and anti-dementia drug use, function in activities of daily living, cognitive function, and prevalence of behavioral and psychological symptoms were collected, using the Multi-Dimensional Dementia Assessment Scale.Results: Of the study population, 1,442 individuals (71%) were prescribed at least one psychotropic drug (antidepressants (49%), anxiolytics, hypnotics, and sedatives (36%), antipsychotics (25%)). Furthermore, 363 individuals (18%) received anti-dementia drugs. Associations between various behavioral and psychological symptoms were found for all psychotropic drug classes and anti-dementia drugs. Verbally disruptive/attention-seeking behavior was associated with all psychotropic drugs. Use of antipsychotics was associated with several behavioral and psychological symptoms, including aggressive behavior.Conclusion: The associations between behavioral and psychological symptoms and psychotropic drug use found in this study indicate that these drugs are prescribed to treat behavioral and psychological symptoms among cognitively impaired individuals despite limited evidence of their efficacy. Given the significant risk of adverse effects among old people with cognitive impairment, it is important to ensure that any medication used is both appropriate and safe.