Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS‐sorted peripheral blood CD4+, CD8+, CD19+, and CD56+cells

Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS‐sorted peripheral blood CD4+, CD8+, CD19+, and CD56+cells
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定量测定 FACS 分选的外周血 CD4+、CD8+、CD19+ 和 CD56+ 细胞中人 MRP1 和 MRP2 mRNA 的表达

DOI:
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发表时间:
2003
影响因子:
3.1
通讯作者:
I. Roots
I. Roots
中科院分区:
医学3区
文献类型:
--
作者:
K. Oselin;P. Mrozikiewicz;R. Pähkla;I. Roots

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目的:ATP结合盒(ABC)转运体挤压各种内源性和外源性化合物。在癌细胞中,它们被认为具有多药耐药性。本研究的目的是确定多药耐药相关蛋白1 (MRP1)和2 (MRP2)在人造血细胞中的表达,它们是ABC转运蛋白家族C亚家族的成员。
Objectives: ATP‐binding cassette (ABC) transporters extrude a wide variety of endogenous and exogenous compounds. In cancer cells, they are known to confer multidrug resistance. The aim of the present study was to determine the expression of the multidrug resistance‐associated protein 1 (MRP1) and 2 (MRP2), which are members of the subfamily C of the ABC transporters family, in human hematopoietic cells.
DOI: 10.1182/blood.v80.11.2729.bloodjournal80112729
发表时间: 1992-12
期刊: Blood
影响因子: 20.3
作者:
D. Drach;Shourong Zhao;J. Drach;R. Mahadevia;Claus Gattringer;Heinz Huber;M. Andreeff
通讯作者: D. Drach;Shourong Zhao;J. Drach;R. Mahadevia;Claus Gattringer;Heinz Huber;M. Andreeff
DOI: 10.1182/blood.v88.5.1747.bloodjournal8851747
发表时间: 1996-09-01
期刊: BLOOD
影响因子: 20.3
作者:
Drach, J;Gsur, A;Huber, H
通讯作者: Huber, H