Time-dependent viscoelastic properties along rat small intestine.
Time-dependent viscoelastic properties along rat small intestine.
复制标题
大鼠小肠的时间依赖性粘弹性。
DOI：
10.3748/wjg.v11.i32.4974
复制
发表时间：
2005
影响因子：
4.3
通讯作者：
H. Gregersen
中科院分区：
文献类型：
--
作者：
James B Smith;Jingbo Zhao;Y. Dou;H. Gregersen
目的
测量小肠张开角变化的时间依赖性（粘弹性）行为，并测试标准线性固体的Kelvin模型对该行为的描述程度。
方法
从10只雌性Wistar大鼠中采集十二指肠、空肠和回肠的节段，并从从这些节段切下的环测量管腔直径、壁厚和随时间的张开角（θ（t））。
结果
形态测量的变化被发现沿着小肠与管腔面积增加和壁厚度从十二指肠到回肠减少。60分钟后获得的开口角在十二指肠中最高（220.8+/-12.9度），并沿肠的长度沿着减小，空肠中为143.9+/-8.9度，回肠中为151.4+/-9.4度。在环被切割后，作为时间函数的开度角的变化很好地拟合于使用方程θ（t）/θ（o）= [-η exp（-λ t）]的开尔文模型。计算的蠕变速率λ在段之间没有差异。与从猪主动脉和冠状动脉计算的常数相比，它表明α吻合良好（在5%以内），eta比血管组织的大3倍，λ在猪冠状动脉值的+/-40%范围内，是猪主动脉值的三分之一。
结论
所有小肠段的张开角随时间的变化符合标准线性弹簧-阻尼器模型。大鼠小肠的粘弹性常数沿其长度沿着是相当均匀的。从本研究中获得的数据增加了小肠生物力学数据的基础集，并提供了与其他组织、患病肠组织或暴露于药物或化学品的肠组织进行比较的参考状态。
AIM
To measure the time-dependent (viscoelastic) behavior in the change of the small intestinal opening angle and to test how well the behavior could be described by the Kelvin model for a standard linear solid.
METHODS
Segments from the duodenum, jejunum, and ileum were harvested from 10 female Wistar rats and the luminal diameter, wall thickness, and opening angle over time (theta(t)) were measured from rings cut from these segments.
RESULTS
Morphometric variations were found along the small intestine with an increase in luminal area and a decrease in wall thickness from the duodenum to the ileum. The opening angle obtained after 60 min was highest in the duodenum (220.8+/-12.9 degrees) and decreased along the length of the intestine to 143.9+/-8.9 degrees in the jejunum and 151.4+/-9.4 degrees in the ileum. The change of opening angle as a function of time, fitted well to the Kelvin model using the equation theta(t)/theta(o) = [-eta exp (-lambda t)] after the ring was cut. The computed creep rate lambda did not differ between the segments. Compared to constant calculated from pig aorta and coronary artery, it showed that alpha agreed well (within 5%), eta was three times larger than that for vascular tissue, and lambda ranged +/-40% from the value of the pig coronary artery and was a third of the value of pig aorta.
CONCLUSION
The change of opening angle over time for all the small intestine segments fits well to the standard linear spring-dashpot model. This viscoelastic constant of the rat small intestine is fairly homogenous along its length. The data obtained from this study add to a base set of biomechanical data on the small intestine and provide a reference state for comparison to other tissues, diseased intestinal tissue or intestinal tissue exposed to drugs or chemicals.
健康人体回肠末端和回盲部括约肌的蠕动。
影响因子：
29.4
作者：
Quigley,EM;Borody,TJ;Phillips,SF;Wienbeck,M;Tucker,RL;Haddad,A
通讯作者：
Haddad,A
在需要静水力工作的条件下，猫肠段进行流体推进。
DOI：
10.1152/ajpgi.1981.240.2.g147
发表时间：
1981
期刊：
The American journal of physiology
影响因子：
--
作者：
Weems,WA;Seygal,GE
通讯作者：
Seygal,GE