Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis.
Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis.
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DOI：
10.1136/bmjopen-2017-018342
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发表时间：
2017-12-29
期刊：
影响因子：
2.9
通讯作者：
Ryg J
中科院分区：
文献类型：
--
作者：
Jepsen DB;Thomsen K;Hansen S;Jørgensen NR;Masud T;Ryg J
研究全身振动锻炼（WBV）对50岁以上成人骨折风险的影响。使用随机效应模型计算相对风险比、跌倒率比和绝对加权平均差的系统综述和荟萃分析。使用I2统计量估计异质性，并使用科克伦协作组的偏差风险工具和GRADE方法来评估证据质量并总结结论。数据库PubMed、Embase和科克伦中心注册库（从成立到2016年4月）以及检索到的出版物的参考列表。随机对照试验，检查WBV对≥ 50岁成人骨折风险的影响。主要结果是骨折，跌倒率和跌倒的参与者比例。次要结果是骨矿物质密度（BMD）、骨微结构、骨转换标志物和跟骨宽带衰减（BUA）。15篇论文（14项试验）符合纳入标准。只有一项研究的骨折数据报告了非显著性骨折减少（风险比（RR）= 0.47，95% CI 0.14 - 1.57，P = 0.22）（中等证据质量）。4项研究（n = 746）显示，WBV降低了福尔斯的发生率，率比为0.67（95% CI 0.50 - 0.89，P = 0.0006; I2 = 19%）（中等证据质量）。此外，3项研究（n = 805）的数据发现福尔斯减少的趋势（RR = 0.76，95% CI 0.48 - 1.20，P = 0.24; I2 = 24%）（证据质量低）。最后，中到低质量的证据显示对BMD没有总体影响，并且关于微结构参数、骨转换标志物和BUA只有稀疏的数据可用。WBV降低跌倒率，但似乎对BMD或微结构没有总体影响。WBV对骨折的影响需要进一步更大规模的充分把握度研究。这项荟萃分析表明，WBV可以通过减少福尔斯来预防骨折。CRD 42016036320;预结果。
To investigate the effect of whole-body vibration exercise (WBV) on fracture risk in adults ≥50 years of age. A systematic review and meta-analysis calculating relative risk ratios, fall rate ratio and absolute weighted mean difference using random effects models. Heterogeneity was estimated using I2 statistics, and the Cochrane Collaboration’s risk of bias tool and the GRADE approach were used to evaluate quality of evidence and summarise conclusions. The databases PubMed, Embase and the Cochrane Central Register from inception to April 2016 and reference lists of retrieved publications. Randomised controlled trials examining the effect of WBV on fracture risk in adults ≥50 years of age. The primary outcomes were fractures, fall rates and the proportion of participants who fell. Secondary outcomes were bone mineral density (BMD), bone microarchitecture, bone turnover markers and calcaneal broadband attenuation (BUA). 15 papers (14 trials) met the inclusion criteria. Only one study had fracture data reporting a non-significant fracture reduction (risk ratio (RR)=0.47, 95% CI 0.14 to 1.57, P=0.22) (moderate quality of evidence). Four studies (n=746) showed that WBV reduced the rate of falls with a rate ratio of 0.67 (95% CI 0.50 to 0.89, P=0.0006; I2=19%) (moderate quality of evidence). Furthermore, data from three studies (n=805) found a trend towards falls reduction (RR=0.76, 95% CI 0.48 to 1.20, P=0.24; I2=24%) (low quality of evidence). Finally, moderate to low quality of evidence showed no overall effect on BMD and only sparse data were available regarding microarchitecture parameters, bone turnover markers and BUA. WBV reduces fall rate but seems to have no overall effect on BMD or microarchitecture. The impact of WBV on fractures requires further larger adequately powered studies. This meta-analysis suggests that WBV may prevent fractures by reducing falls. CRD42016036320; Pre-results.
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影响因子：
4
作者：
Gomez-Cabello, Alba;Gonzalez-Agueero, Alejandro;Vicente-Rodriguez, German
通讯作者：
Vicente-Rodriguez, German
影响因子：
4
作者：
Buckinx, F.;Beaudart, C.;Bruyere, O.
通讯作者：
Bruyere, O.
影响因子：
4
作者：
Leung, K. S.;Li, C. Y.;Cheung, W. H.
通讯作者：
Cheung, W. H.
影响因子：
2.3
作者：
Gusi, Narcis;Raimundo, Armando;Leal, Alejo
通讯作者：
Leal, Alejo
影响因子：
4.1
作者：
Beaudart C;Maquet D;Mannarino M;Buckinx F;Demonceau M;Crielaard JM;Reginster JY;Bruyère O
通讯作者：
Bruyère O