Prevalence of Depression Among Women of Reproductive Age in the United States
Prevalence of Depression Among Women of Reproductive Age in the United States
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DOI：
10.1097/aog.0000000000002535
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发表时间：
2018-04-01
影响因子：
7.2
通讯作者：
Butwick, Alexander
中科院分区：
文献类型：
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作者：
Guo, Nan;Robakis, Thalia;Butwick, Alexander
目的：描述非妊娠育龄妇女中抑郁症的患病率、抗抑郁药的使用情况以及重度和轻度抑郁症的预测因素。方法：使用2007-2014年国家健康与营养检查调查的数据，我们对3,705名非妊娠育龄妇女进行了一项横断面研究。主要结果是重度抑郁症的患病率，次要结果是轻度抑郁症的患病率，抗抑郁药的使用率，以及重度和轻度抑郁症的预测因子。使用患者健康问卷9对重度和轻度抑郁症进行分类。结果：抑郁症的总患病率分别为4.8%（95%CI 4.0-5.7%）和4.3%（95%CI 3.5-5.2%）。重度抑郁症和轻度抑郁症女性中抗抑郁药使用的患病率分别为32.4%（95%CI 25.3-40.4%）和20.0%（95%CI 12.9-29.7%）。与抑郁症最密切相关的因素是政府保险（调整的相对危险度[RR]比2.49，95% CI 1.56-3.96）和高血压（调整后RR 2.09，95% CI 1.25-3.50）;对于轻度抑郁症，这些人的教育程度低于高中（校正后的RR 4.34，95% CI 2.09-9.01）或高中文化程度（校正后的RR 2.92，95% CI 1.35-6.31）。三分之一的重度抑郁症患者和五分之一的轻度抑郁症患者使用抗抑郁药。
OBJECTIVE: To describe the prevalence, use of antidepressants, and predictors of major and minor depression among nonpregnant women of childbearing age.METHODS: Using data from the National Health and Nutrition Examination Surveys 2007-2014, we performed a cross-sectional study of 3,705 nonpregnant women of childbearing age. The primary outcome is the prevalence of major depression, and secondary outcomes are the prevalence of minor depression, rates of antidepressant use, and predictors of major and minor depression. Major and minor depression were classified using the Patient Health Questionnaire 9. Univariate and multivariate associations between major depression and minor depression with potential predictors were estimated using multinomial logistic regression.RESULTS: The overall prevalences of major and minor depression were 4.8% (95% CI 4.0-5.7%) and 4.3% (95% CI 3.5-5.2%), respectively. The prevalences of antidepressant use among women with major depression and minor depression were 32.4% (95% CI 25.3-40.4%) and 20.0% (95% CI 12.9-29.7%), respectively. Factors most strongly associated with major depression were government insurance (adjusted relative risk [RR] ratio 2.49, 95% CI 1.56-3.96) and hypertension (adjusted RR 2.09, 95% CI 1.25-3.50); for minor depression, these were education less than high school (adjusted RR 4.34, 95% CI 2.09-9.01) or high school education (adjusted RR 2.92, 95% CI 1.35-6.31).CONCLUSION: Our analysis indicates that 1 in 20 nonpregnant women of childbearing age experience major depression. Antidepressants are used by one third of those with major depression and one fifth of those with minor depression.