A broadband LED source in visible to short-wave-infrared wavelengths for spectral tumor diagnostics
A broadband LED source in visible to short-wave-infrared wavelengths for spectral tumor diagnostics
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DOI：
10.1063/1.4985015
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发表时间：
2017-06-05
影响因子：
4
通讯作者：
Schleipen, Jean
中科院分区：
文献类型：
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作者：
Hayashi, Daiyu;van Dongen, Anne Marie;Schleipen, Jean
各种肿瘤类型在可见光，特别是近短波红外波长范围内的吸收和反射光谱中表现出光谱指纹。为了通过漫反射光谱进行光谱肿瘤诊断的目的，我们开发了一种宽带发光二极管（LED）源，其由用于光激发的蓝色LED、用于可见光至近红外发射的Lu 3Al 5 O 12：Ce 3+，Cr 3+发光石榴石和用于近红外至短波红外发射的铋掺杂GeO 2发光玻璃组成。它在470-1600 nm连续发射宽带光，光谱间隙在900-1000 nm。与目前可用的宽带光源如卤素灯、高压放电灯和超连续谱激光器相比，本文的光源在高光谱稳定性、改善的光耦合到光纤、低光源成本和实现电池驱动的潜力方面具有用于光谱组织诊断的显著优势。出版社：AIP Publishing
Various tumor types exhibit the spectral fingerprints in the absorption and reflection spectra in visible and especially in near-to short-wave-infrared wavelength ranges. For the purpose of spectral tumor diagnostics by means of diffuse reflectance spectroscopy, we developed a broadband light emitting diode (LED) source consisting of a blue LED for optical excitation, Lu3Al5O12: Ce3+, Cr3+ luminescent garnet for visible to near infrared emissions, and Bismuth doped GeO2 luminescent glass for near-infrared to short-wave infrared emissions. It emits broad-band light emissions continuously in 470-1600 nm with a spectral gap at 900-1000 nm. In comparison to the currently available broadband light sources like halogen lamps, high-pressure discharge lamps and super continuum lasers, the light sources of this paper has significant advantages for spectral tissue diagnostics in high-spectral stability, improved light coupling to optical fibers, potential in low light source cost and enabling battery-drive. Published by AIP Publishing.