EFFERENT PROJECTIONS FROM THE SUBNUCLEUS-RETICULARIS-DORSALIS (SRD) - A PHASEOLUS-VULGARIS LEUKOAGGLUTININ STUDY IN THE RAT
EFFERENT PROJECTIONS FROM THE SUBNUCLEUS-RETICULARIS-DORSALIS (SRD) - A PHASEOLUS-VULGARIS LEUKOAGGLUTININ STUDY IN THE RAT
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DOI：
10.1016/0304-3940(90)90083-l
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发表时间：
1990-08-24
影响因子：
2.5
通讯作者：
LEBARS, D
中科院分区：
文献类型：
--
作者：
BERNARD, JF;VILLANUEVA, L;LEBARS, D
本文应用微量离子导入法研究了大鼠延髓尾侧网状结构中一个限制性区域--网状背侧亚核（subnucleus reticularis dorsalis，SRD）的传出投射。结果发现，SRD的纤维主要投射到脊髓、口腔运动核、背侧副下橄榄核、网状结构的小细胞核和小细胞核以及丘脑的束旁核和腹正中核。结合我们先前的电生理研究结果，本研究表明，SRD可能参与疼痛处理的控制和由伤害性事件引起的运动反应。
Small iontophoretic applications of Phaseolus vulgaris leucoagglutinin (PHA-L) were used in rats to study the efferent projections from a restricted region in the reticular formation of the caudal medulla: the subnucleus reticularis dorsalis (SRD). It was found that fibres from SRD project mainly to the spinal cord, the oral motor nuclei, the dorsal accessory inferior olive, the giganto- and parvo-cellular nuclei of the reticular formation and the parafascicular and ventromedian nuclei of the thalamus. Together with our previous electrophysiological findings, this study suggests that the SRD could be involved both in the control of pain processing and in motor reactions elicited by noxious events.