Urban/rural differences in prevalence and risk factors for intestinal helminth infection in southern Malawi
Urban/rural differences in prevalence and risk factors for intestinal helminth infection in southern Malawi
复制标题
DOI：
10.1080/00034983.2000.11813553
复制
发表时间：
2000-06-01
影响因子：
--
通讯作者：
Ssembatya-Lule, G
中科院分区：
文献类型：
--
作者：
Phiri, K;Whitty, CJM;Ssembatya-Lule, G
城市化可能会增加人类感染肠道蠕虫的风险。一项横断面调查旨在调查马拉维南部类似城乡社区 3-14 岁儿童感染此类感染的患病率、强度和潜在危险因素。采集了 553 名儿童（273 名城市儿童和 280 名农村儿童）的粪便样本。城市人群蠕虫感染总体患病率显着高于农村（16.5% vs. 3.6%；P < 0.001），这主要是由于蛔虫感染患病率存在差异。生活在城市社区与明显较高的感染风险相关[比值比 (OR) = 5.3； 95% 置信区间 (CI) = 2.6-12.1]，即使在控制了潜在的混杂因素之后也是如此。在城市社区，危险因素包括房屋周围有水/污水池（OR = 3.0；CI = 1.4-6.5）、不穿鞋（OR = 7.1；CI = 2.7-19.2）、不上学（OR = 2.8；CI = 1.2-6.5）、母亲受过4-8年教育（OR = 5.2；CI = 2.0-14.0），母亲年龄低于 35 岁（OR = 4.09；CI = 1.39-16.28）。在非洲这一地区，减少蠕虫感染的努力最好集中于减少城市地区的土蠕虫负担。
Urbanization may increase the risk of human infection with intestinal helminths. A cross-sectional survey was conducted to investigate the prevalence, intensity and potential risk factors of acquiring such infection, among children aged 3-14 years in similar urban and rural communities in southern Malawi. Stool samples were collected from 553 children (273 urban and 280 rural). The overall prevalence of helminth infection was significantly higher in the urban subjects than in the rural (16.5% v. 3.6%; P < 0.001), mostly because of differences in the prevalence of Ascaris lumbricoides infection. Living in an urban community was associated with a significantly higher risk of infection [odds ratio (OR) = 5.3; 95% confidence interval (CI) = 2.6-12.1], even after controlling for potential confounding factors. In the urban community, risk factors included having pools of water/sewage around houses (OR = 3.0; CI = 1.4-6.5), not wearing shoes (OR = 7.1; CI = 2.7-19.2), not attending school (OR = 2.8; CI = 1.2-6.5), having mothers with 4-8 years of education (OR = 5.2; CI = 2.0-14.0), and having mothers below 35 years of age (OR = 4.09; CI = 1.39-16.28). In this part of Africa, efforts to reduce helminth infections may best be focused on reducing geohelminth burden in urban areas.