Cerebrospinal Fluid Levels of MHPG in Affective Disorders

Cerebrospinal Fluid Levels of MHPG in Affective Disorders
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情感障碍患者脑脊液中 MHPG 水平

DOI:
10.1038/235440a0
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发表时间:
1972
期刊:
影响因子:
64.8
通讯作者:
M. Suhl
M. Suhl
中科院分区:
综合性期刊1区
文献类型:
--
作者:
S. Wilk;B. Shopsin;S. Gershon;M. Suhl

文献摘要

被引文献

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情感障碍的儿茶酚胺假说 1,2 将功能性儿茶酚胺减少与抑郁症联系起来,已通过测量血浆或尿液中的去甲肾上腺素 (NA) 或尿液中的 NA 代谢物、去甲肾上腺素和 VMA 3-5 进行了检验。这些化合物中可能只有一小部分源自中枢神经系统6,因此这导致了相互矛盾的结果也就不足为奇了。
THE catecholamine hypothesis of affective disorders1,2, which associates decreased functional catecholamines with depression, has been tested by measurement of noradrenaline (NA) in plasma or urine or the NA metabolites, normetanephrine and VMA in urine3–5. Probably only a small percentage of these compounds originate from the central nervous system6, and so it is not surprising that this has led to conflicting results.