Ambulatory blood pressure after acute exercise in older men with essential hypertension.
Ambulatory blood pressure after acute exercise in older men with essential hypertension.
复制标题
患有原发性高血压的老年男性急性运动后的动态血压。
DOI：
10.1016/s0895-7061(99)00141-7
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发表时间：
2000
影响因子：
3.2
通讯作者：
Hagberg,JM
中科院分区：
文献类型：
--
作者：
Taylor-Tolbert,NS;Dengel,DR;Brown,MD;McCole,SD;Pratley,RE;Ferrell,RE;Hagberg,JM
我们试图确定高血压患者在剧烈运动后血压的降低是否能持续超过在受控实验室环境中发现的 2 至 3 小时。受试者 (n 11) 是肥胖（32 ± 4% 体脂）、久坐 (VO2max27 ± 4 mL/kg/min) 的 60 ± 6 岁男性，患有 1 期或 2 期原发性高血压。在进行 45 分钟 70% VO2max 跑步机锻炼之前的 1 天和未进行锻炼的另一天记录动态血压。与之前没有运动的当天相比，运动后前 16 小时的收缩压降低了 6 至 13 mm Hg (P< .05)。运动后一天的二十四小时、白天和夜间平均收缩压显着降低。在整个 24 小时和记录的白天部分中，峰值收缩压有降低的趋势；运动后记录的夜间部分收缩压峰值显着降低。运动后整个 24 小时和白天记录部分的收缩压负荷（收缩压读数> 140 mm Hg 的百分比）有所降低。与之前没有运动的当天相比，急性运动后前 16 小时中有 12 小时（第 0 至 4、5 至 8、13 至 16 小时）舒张压较低 (P< .05)。运动后记录的二十四小时、白天和夜间平均舒张压也显着降低。整个 24 小时内舒张压峰值较低。运动后整个 24 小时和一天中的部分时间舒张压负荷（舒张压读数>90 mm Hg 的百分比）较低。初步数据还表明，血管紧张素原、脂蛋白脂肪酶和血管紧张素转化酶位点的常见遗传多态性可能会影响急性运动后的降压反应。因此，对于久坐的肥胖高血压男性来说，一次有氧运动足以降低血压，从而显着降低 24 小时平均收缩压、舒张压和平均动脉压。这可能会导致老年高血压男性在急性运动后 24 小时内心血管负荷减轻。 Am J Hypertens 2000；13:44–51 © 2000 American Journal of Hypertension, Ltd.
We sought to determine whether reductions in blood pressure in hypertensives after acute exercise persist for more than the 2 to 3 h found in controlled laboratory settings. Subjects (n 11) were obese (32 ± 4% body fat), sedentary (VO2max27 ± 4 mL/kg/min) 60 ± 6-year-old men with stage 1 or 2 essential hypertension. Ambulatory blood pressure was recorded on 1 day preceded by 45 min of 70% VO2maxtreadmill exercise and on another day not preceded by exercise. Systolic blood pressure was lower by 6 to 13 mm Hg for the first 16 h after exercise (P< .05) compared to the day without prior exercise. Twenty-four-hour, day, and night average systolic blood pressures were significantly lower on the day after exercise. There was a trend for peak systolic blood pressure to be lower during the entire 24 h and the day portion of the recording; peak systolic blood pressure was significantly lower during the night portion of the recording after exercise. Systolic blood pressure load (percent of systolic blood pressure readings > 140 mm Hg) was reduced during the entire 24 h and the day portion of the recording after exercise. Diastolic blood pressure was lower for 12 of the first 16 h after acute exercise (hours 0 to 4, 5 to 8, 13 to 16) (P< .05) compared to the day without prior exercise. Twenty-four-hour, day, and night average diastolic blood pressure was also significantly lower on the recording after exercise. Peak diastolic blood pressure was lower over the entire 24-h period. Diastolic blood pressure load (percent of diastolic blood pressure readings >90 mm Hg) was lower during the entire 24 h and the day portion of the day after exercise. Preliminary data also suggest that common genetic polymorphisms at the angiotensinogen, lipoprotein lipase, and angiotensin converting enzyme loci may affect the blood pressure-lowering response after acute exercise. Thus, in sedentary, obese hypertensive men a single aerobic exercise session reduced blood pressure enough to result in significantly lower 24-h average systolic, diastolic, and mean arterial blood pressure. This could result in a reduced cardiovascular load during the 24 h after acute exercise in older hypertensive men. Am J Hypertens 2000;13:44–51 © 2000 American Journal of Hypertension, Ltd.