Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity
Effect of weight loss on the retinochoroidal structural alterations among patients with exogenous obesity
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DOI：
10.1371/journal.pone.0235926
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发表时间：
2020-07-09
期刊：
影响因子：
3.7
通讯作者：
Gupta, Vishali
中科院分区：
文献类型：
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作者：
Agarwal, Aniruddha;Saini, Arshiya;Gupta, Vishali
目的利用扫源光学相干断层扫描（SS-OCT）和OCT血管造影（OCTA）评估外源性肥胖患者视网膜脉络膜血管的变化。 方法本前瞻性研究纳入60例诊断为肥胖的患者（47名男性）（平均年龄：46.47+/-10.9岁），其中30例接受减肥手术（A组），30例接受保守治疗。管理（运动/饮食）（B 组）。在基线和三个月随访时测量参数包括脉络膜厚度（CT）、脉络膜血管指数（CVI）和视网膜毛细血管密度指数（CDI）和动静脉比率（AVR）。纳入正常参与者的 30 只眼睛（30 名年龄和性别匹配）进行比较。结果与对照组相比，60 名肥胖参与者的基线 CT 较低。与正常受试者相比，肥胖受试者的平均 CVI 较高（0.66 +/- 0.02 对比 0.63 +/- 0.04；p
PurposeTo evaluate the changes in the retinochoroidal vasculature in patients with exogenous obesity using swept-source optical coherence tomography (SS-OCT) and OCT angiography (OCTA).MethodsIn this prospective study, 60 patients diagnosed with obesity (47 males) (mean age: 46.47 +/- 10.9 years) were included, of which 30 patients underwent bariatric surgery (Group A), and 30 patients underwent conservative management (exercise/diet) (Group B). Parameters including choroidal thickness (CT), choroidal vascularity index (CVI) and retinal capillary density index (CDI) and arteriovenous ratio (AVR) were measured at the baseline and three months follow up. 30 eyes (30 age and gender-matched) of normal participants were included for comparison.ResultsBaseline CT was lower in 60 participants with obesity compared to controls. Compared with normal subjects, subjects with obesity had higher mean CVI (0.66 +/- 0.02 versus 0.63 +/- 0.04; p