Duane retraction syndrome.
Duane retraction syndrome.
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DOI：
10.1016/s0896-1549(05)70238-8
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发表时间：
2001-09-01
期刊：
影响因子：
--
通讯作者：
Saunders, R A
中科院分区：
文献类型：
--
作者：
Alexandrakis, G;Saunders, R A
Duane眼球退缩综合征（DRS）是由眼球水平运动不足、眼睑退缩、睑裂变窄和眼球垂直运动异常所组成。大多数病例为散发性和单侧（通常为左侧），女性略占优势。在DRS患者中描述了几种相关的眼部和全身疾病。在大多数情况下，外展神经核和神经缺失或发育不良，外直肌由眼神经的分支支配。但是，可能存在机械异常。I型DRS（原发性凝视位内斜视伴外展受限）占大多数病例。大约50%的I型DRS患者在主注视时是正眼位的。内斜视是最常见的斜视类型，内收时会出现特征性的上枝和下枝。手术干预已逐渐变得越来越流行，以改善主要的凝视对准和减轻一些相关的异常，在眼球运动。然而，患者很少表现出临床正常，有限的期望是适当的。
Duane retraction syndrome (DRS) consists of deficient horizontal eye movements, eyelid retraction, palpebral fissure narrowing, and abnormal vertical eye movements. Most cases are sporadic and unilateral (usually left side) with a slight female predominance. Several associated ocular and systemic conditions have been described in DRS patients. In most cases, the abducens nucleus and nerve are absent or hypoplastic, and the lateral rectus muscle is innervated by a branch of the oculomotor nerve. However, there may be contributing mechanical abnormalities. Type I DRS (primary gaze position esotropia with limitation of abduction) comprises the majority of cases. Approximately 50% of type I DRS patients are orthophoric in primary gaze. Esotropia is the most common type of strabismus encountered, and characteristic up shoots and down shoots occur in adduction. Surgical intervention has gradually become more popular in order to improve the primary gaze alignment and mitigate some of the associated abnormalities in ocular motility. However, patients are rarely rendered clinically normal, and limited expectations are appropriate.