Obesity as a risk factor in venous thromboembolism
Obesity as a risk factor in venous thromboembolism
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DOI：
10.1016/j.amjmed.2005.03.012
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发表时间：
2005-09-01
影响因子：
5.9
通讯作者：
Olson, RE
中科院分区：
文献类型：
--
作者：
Stein, PD;Beernath, A;Olson, RE
目的：肥胖是否是肺栓塞或深静脉血栓形成的独立危险因素尚未完全确定。方法：我们利用全国医院出院调查数据库进一步调查肥胖在静脉血栓栓塞性疾病中的潜在风险。结果：肥胖患者与非肥胖患者相比，深静脉血栓形成的相对风险为2.50（95%置信区间[CI] = 2.49-2.51）。肺栓塞的相对风险为2.21 (95% CI = 2.20-2.23)。肥胖女性发生深静脉血栓的相对风险高于肥胖男性，分别为 2.75 (95% CI = 2.74-2.76) 和 2.02 (95% CI = 2.01-2.04)。肥胖对 40 岁以下的男性和女性影响最大。结论：数据表明，肥胖是男性和女性静脉血栓栓塞性疾病的危险因素。 (c) 2005 Elsevier Inc. 保留所有权利。
PURPOSE: Whether obesity is an independent risk factor for pulmonary embolism or deep venous thrombosis has not been fully determined.METHODS: We used the database of the National Hospital Discharge Survey to further investigate the potential risk of obesity in venous thromboembolic disease.RESULTS: The relative risk of deep venous thrombosis, comparing obese patients with non-obese patients, was 2.50 (95% confidence interval [CI] = 2.49-2.51). The relative risk of pulmonary embolism was 2.21 (95% CI = 2.20-2.23). Obese females had a greater relative risk for deep venous thrombosis than obese males, 2.75 (95% CI = 2.74-2.76) versus 2.02 (95% CI = 2.01-2.04). Obesity had the greatest impact on both men and women aged less than 40 years.CONCLUSION: The data indicate that obesity is a risk factor for venous thromboembolic disease in men as well as women. (c) 2005 Elsevier Inc. All rights reserved.