Associations between sexual partner number and HIV risk behaviors: implications for HIV prevention efforts in a Treatment as Prevention (TasP) environment.

Associations between sexual partner number and HIV risk behaviors: implications for HIV prevention efforts in a Treatment as Prevention (TasP) environment.
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DOI:
10.1080/09540121.2018.1454583
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发表时间:
2018-10
期刊:
影响因子:
1.7
通讯作者:
Hogg RS
Hogg RS
中科院分区:
医学4区
文献类型:
--
作者:
Armstrong HL;Roth EA;Rich A;Lachowsky NJ;Cui Z;Sereda P;Card KG;Jollimore J;Howard T;Moore DM;Hogg RS

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先前的研究表明,同性恋和双性恋男性(GBM)的性伴侣明显多于同龄异性恋男性和女性。因此,一些艾滋病毒干预项目侧重于减少伴侣。然而,新的研究结果质疑性伴侣数量作为GBM给予治疗预防(TasP)计划和新的血清适应策略的性风险度量的相关性,这些策略导致降低GBM社区病毒载量和新的HIV预防行为。为了评估性伴侣数量是否仍然是生活在积极推动TasP作为省级政策的城市中的GBM性风险的重要衡量标准,我们分析了加拿大温哥华通过受访者驱动抽样招募的719 GBM的横截面数据。多变量负二项回归分析显示,性伴侣数量与先前确定的艾滋病毒风险因素显著相关,包括与血清状态不一致和/或未知的性伴侣进行无安全套肛交、使用性玩具、参加群体性活动、接受性交易金钱和性药物使用。这些结果表明,性伴侣数量仍然是一个重要的近似艾滋病毒风险指标。然而,需要对艾滋病毒治疗状况采取更细致的措施,并更好地了解GBM中伴侣数量增加的可能原因。
Previous research indicates that gay and bisexual men (GBM) have significantly more sexual partners than same-aged heterosexual men and women. As a result, some HIV intervention programs have focused on partner reduction. However, new research findings question the relevance of sexual partner number as a sexual risk measure for GBM given Treatment as Prevention (TasP) programs and new seroadaptive strategies which have led to lower GBM community viral load and new HIV prevention behaviors. To assess if sexual partner number continues to remain an important measure of sexual risk for GBM living in a city that actively promotes TasP as provincial policy, we analysed cross-sectional data from 719 GBM recruited through respondent-driven sampling in Vancouver, Canada. Multivariable negative binomial regression analysis showed that partner number was significantly associated with previously identified HIV risk factors including condomless anal intercourse with serodiscordant and/or unknown serostatus partners, using sex toys, attending group sex events, receiving money for sex, and sex drug use. These results indicate that sexual partner number remains an important proximate HIV risk measure. However, more nuanced measures of HIV treatment status and greater understanding of the possible causes of increased partner number among GBM are needed.
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