Availability of antibiotics as over-the-counter drugs in pharmacies: a threat to public health in Vietnam
Availability of antibiotics as over-the-counter drugs in pharmacies: a threat to public health in Vietnam
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DOI：
10.1046/j.1365-3156.1997.d01-213.x
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发表时间：
1997-12-01
影响因子：
3.3
通讯作者：
Van Le, T
中科院分区：
文献类型：
--
作者：
Duong, DV;Binns, CW;Van Le, T
在越南河内的Badinh区进行了一项关于通过零售药店购买的抗生素使用情况的调查。调查发现，购买者在他们或那些认为需要抗生素的人出现咳嗽（34.1%），喉咙痛（32.5%），胃部不适（10.0%）和腹泻（8.8%）等轻微症状时会前往药房。最常购买的抗生素是氨苄西林（31.1%）、阿莫西林（16.7%）、复方新诺明（11.6%）、四环素（5.2%）和头孢氨苄（4.8%）。购买量中位数为10片，平均11.34片（95%CI 9.65-12.97）。大约30%的购买者打算服用抗生素3天或更短时间，平均购买抗生素的费用为1.27美元（95%CI 1.06-1.39）。未服用完整疗程抗生素的主要原因不是经济上的限制，而是购买者对抗生素的认识不足。Logistic回归分析表明，购买者的年龄，症状的长度和使用的治疗前访问一家药店可以作为预测变量的决定购买抗生素优先于替代药物。当疾病持续超过一周且尚未服用抗生素时，可使用抗生素。抗生素也是年轻人而不是老年人购买的。该研究表明，需要更好地对公众进行合理使用抗生素的健康教育。
A survey on the use of antibiotics purchased through retail pharmacies was conducted in the Badinh district of Hanoi, Vietnam. The survey found that purchasers visit a pharmacy when they or those who felt they needed antibiotics had minor symptoms such as cough (34.1%), sore throat (32.5%), stomach upsets (10.0%) and diarrhoea (8.8%). The most often purchased antibiotics were ampicillin (31.1%), amoxyllin (16.7%), cotrimoxazol (11.6%), tetracycline (5.2%) and cephalexin (4.8%). The median of the purchased quantity was 10 tablets, the mean 11.34 tablets (95% CI 9.65-12.97). About 30% of the purchasers intended to take antibiotics for three days or less. The mean cost of a antibiotic purchase was US$1.27 (95% CI 1.06-1.39). The main reason for not taking a full course of antibiotics was not economic constraint, but the purchasers' poor knowledge about antibiotics. Logistic regression analysis indicates that age of purchasers, length of symptoms and kinds of treatment used before visiting a pharmacy could be used as predictive variables for the decision to buy antibiotics in preference to alternative drugs. Antibiotics are used when illness lasts longer than one week and antibiotics have not yet been taken. Antibiotics are also purchased by young rather than old people. The study documents the need for better health education about the rational use of antibiotics in the general public.