Surgical treatment of cardiac tumors: a 5-year experience from a single cardiac center

Surgical treatment of cardiac tumors: a 5-year experience from a single cardiac center
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心脏肿瘤的手术治疗:单个心脏中心的 5 年经验

DOI:
10.21037/jtd.2016.03.87
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发表时间:
2016-05-01
影响因子:
2.5
通讯作者:
Wang, Zhinong
Wang, Zhinong
中科院分区:
医学4区
文献类型:
--
作者:
Yin, Liang;He, Dengke;Wang, Zhinong

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背景:心脏肿瘤是一种罕见的肿瘤,临床表现多样,常引起意外症状或猝死。方法:回顾性分析2008年1月至2013年12月在我院心脏病中心接受手术治疗的所有心脏肿瘤患者的病历资料,分析其临床表现、组织病理学谱、死亡率和随访资料。我们的研究回顾了临床病史、围手术期数据、手术结果、疗效和随访数据。根据肿瘤在心脏中的部位分布将患者分为两组。结果:共有131例接受心脏肿瘤手术治疗的患者入选本研究,平均年龄为51.39 ± 16.37岁。结果显示,原发性心内肿瘤104例(79.47%)为良性,21例(16.03%)为原发性恶性,6例(4.6%)为转移性心内肿瘤。术后1、3、5年生存率分别为83.20%、78.62%、66.41%。除性别(P=0.002)、体表面积(P =0.045)和体重(P=0.033)外,左、右心肿瘤患者的基本特征相似。与右心肿瘤患者相比,左心肿瘤患者的CPB时间显著延长(P
Background: Cardiac tumors are rare but manifested with various clinical presentations and often cause unexpected symptoms or sudden death. The objective is to review the clinical presentation, histopathological spectrum, mortality and follow-up data of patients with cardiac tumors following surgery treatment over a period of 5 years.Methods: We retrospectively collected the medical records of all patients diagnosed of cardiac tumors in the period between January 2008 and December 2013 at the cardiac center of our university. Clinical histories, perioperative data, surgical findings, efficacy and follow-up data were reviewed in our study. Patients were divided into two groups according to site distribution of the tumors in the heart.Results: A total of 131 patients underwent surgical treatment of cardiac tumors were enrolled in this study, with a mean age of 51.39 +/- 16.37. The result of analysis showed that 79.47% (n=104) of the primary intracardiac tumors were benign, while primary malignant neoplasms accounted for 16.03% (n=21) of all patients, with the remainder (n=6, 4.6%) metastatic tumors transferred from other organs. Among all patients there were 2 in-hospital deaths and the survival rate in all patients at 1-year, 3-year and 5-year follow up was 83.20%, 78.62% and 66.41% respectively. Both patients with tumors in the left and right heart had similar basic characteristics except sex gender (P=0.002), BSA (P=0.045) and weight (P=0.033). Compared with patients with tumors in the right heart, patients with tumors in the left heart had significant higher CPB time (P