The Impact of Parkinson's Disease on Breath Pauses and Their Relationship to Speech Impairment: A Longitudinal Study.
The Impact of Parkinson's Disease on Breath Pauses and Their Relationship to Speech Impairment: A Longitudinal Study.
复制标题
帕金森病对呼吸暂停的影响及其与言语障碍的关系：一项纵向研究。
DOI：
10.1044/2020_ajslp-20-00003
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发表时间：
2020
影响因子：
2.6
通讯作者：
Huber,JessicaE
中科院分区：
文献类型：
--
作者：
Darling-White,Meghan;Huber,JessicaE
目的：本纵向研究的目的是：(a)检查帕金森病（PD）进展对呼吸暂停模式和语言和语言错误的影响；(b)确定呼吸暂停和语言和语言错误对语言障碍的影响程度。方法8名PD患者和8名年龄和性别匹配的对照组参与者在两次（时间1和时间2）中平均间隔3年7个月阅读一篇文章。两名语言病理学家每次都会对所有参与者的语言障碍程度进行评估。因变量包括相对于语法和标点符号的每次呼吸暂停的位置，以及不流畅和迷宫的数量。结果时间1时，两组间呼吸暂停模式无显著差异。在时间2，PD患者在主要语法边界和句号处的呼吸停顿明显少于对照组，而在没有标点符号的位置的呼吸停顿明显多于对照组。PD患者在两个时间点产生的不流畅性明显多于对照组。在任何时间点，两组之间产生的迷宫数量都没有显著差异。在没有标点符号的地方，迷宫的数量和呼吸停顿的百分比一起解释了与语言障碍严重程度评级相关的50%的差异。结论这些结果强调了同时针对呼吸生理和认知语言系统来改善PD患者言语产生的重要性。
PurposeThe purposes of this longitudinal study were to (a) examine the impact of Parkinson's disease (PD) progression on breath pause patterns and speech and linguistic errors and (b) determine the extent to which breath pauses and speech and linguistic errors contribute to speech impairment.MethodEight individuals with PD and eight age- and sex-matched control participants produced a reading passage on two occasions (Time 1 and Time 2) 3 years and 7 months apart on average. Two speech-language pathologists rated the severity of speech impairment for all participants at each time. Dependent variables included the location of each breath pause relative to syntax and punctuation as well as the number of disfluencies and mazes.ResultsAt Time 1, there were no significant differences between the groups regarding breath pause patterns. At Time 2, individuals with PD produced significantly fewer breath pauses at major syntactic boundaries and periods as well as significantly more breath pauses at locations with no punctuation than control participants. Individuals with PD produced a significantly greater number of disfluencies than control participants at both time points. There were no significant differences between the groups in the number of mazes produced at either time point. Together, the number of mazes and the percentage of breath pauses at locations with no punctuation explained 50% of the variance associated with the ratings of severity of speech impairment.ConclusionThese results highlight the importance of targeting both respiratory physiological and cognitive–linguistic systems in order to improve speech production in individuals with PD.