A PROSPECTIVE LONGITUDINAL-STUDY OF DEPRESSION, COGNITIVE DECLINE, AND PHYSICAL IMPAIRMENTS IN PATIENTS WITH PARKINSONS-DISEASE
A PROSPECTIVE LONGITUDINAL-STUDY OF DEPRESSION, COGNITIVE DECLINE, AND PHYSICAL IMPAIRMENTS IN PATIENTS WITH PARKINSONS-DISEASE
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DOI：
10.1136/jnnp.55.5.377
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发表时间：
1992-05-01
影响因子：
11
通讯作者：
ROBINSON, RG
中科院分区：
文献类型：
--
作者：
STARKSTEIN, SE;MAYBERG, HS;ROBINSON, RG
对 105 名帕金森病患者进行了连续一系列检查，检查是否存在情感障碍、认知缺陷和日常生活活动 (ADL) 障碍；初次检查 12 个月后，92 人接受了相同的评估。 根据最初的精神病学发现，患者被分为重度抑郁症组、轻度抑郁症组和非抑郁症组。 Patients with major depression showed a significantly greater cognitive decline, deterioration in ADLs, and further advance through the Hoehn and Yahr stages than patients with either minor depression or no depression.
A consecutive series of 105 patients with Parkinson's disease were examined for the presence of affective disorders, cognitive deficits, and impairments in activities of daily living (ADLs); 92 received the same evaluation 12 months after the initial examination. On the basis of the initial psychiatric findings, patients were divided into major, minor, and non-depressed groups. Patients with major depression showed a significantly greater cognitive decline, deterioration in ADLs, and further advance through the Hoehn and Yahr stages than patients with either minor depression or no depression.