Systemic amyloidosis following ankylosing spondylitis associated with congestive heart failure. A case report.
Systemic amyloidosis following ankylosing spondylitis associated with congestive heart failure. A case report.
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强直性脊柱炎后的系统性淀粉样变性与充血性心力衰竭相关。
DOI：
10.1536/ihj.36.681
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Yoshio Uehara
中科院分区：
文献类型：
--
作者：
T. Fujito;Teruo Inoue;K. Hoshi;H. Hatano;H. Kamishirado;K. Takayanagi;Terumi Hayashi;S. Morooka;Yutaka Takabatake;Yoshio Uehara
我们报告的情况下，38岁的男子谁开发致命的，系统性淀粉样变性强直性脊柱炎。他因充血性心力衰竭的症状入院。根据腮腺活检和超声心动图，他被诊断为活动性强直性脊柱炎后系统性淀粉样变性。然而，临床过程迅速进展，最终患者死于急性坏死性胰腺炎。迄今为止，全世界报告的病例数量有限。文献报道淀粉样变性的局部病变和良性临床过程。这是日本的第一份报告，表明强直性脊柱炎相关的淀粉样变性可能表现出快速进展的临床过程，从而表明在这种情况下，需要精心治疗。
We report the case of a 38-year-old man who developed fatal, systemic amyloidosis following ankylosing spondylitis. He was admitted for symptoms of congestive heart failure. Based on parotid gland biopsy and echocardiography, he was diagnosed as having systemic amyloidosis following active ankylosing spondylitis. However, the clinical course was rapidly progressive and eventually the patient died of acute necrotizing pancreatitis. The association has been reported thus far in a limited number of cases worldwide. The literature has featured localized lesions and a benign clinical course of the amyloidosis. This case, the first report from Japan, indicates that the amyloidosis associated with ankylosing spondylitis might exhibit a rapidly progressive clinical course, thereby suggesting that in such a case, meticulous treatment is required.