Pyloric gland-type tubular adenoma superimposed on intraductal papillary mucinous tumor of the pancreas

Pyloric gland-type tubular adenoma superimposed on intraductal papillary mucinous tumor of the pancreas
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幽门腺型管状腺瘤叠加于胰腺导管内乳头状粘液性肿瘤

DOI:
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发表时间:
2002
期刊:
影响因子:
3.5
通讯作者:
T. Motoyama
T. Motoyama
中科院分区:
医学3区
文献类型:
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作者:
N. Kato;Sunao Akiyama;T. Motoyama

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抽象的。我们报告一例罕见的主胰管幽门腺型管状腺瘤。这是一个肉眼可见的息肉状结节,由紧密排列的幽门型腺体组成。腺瘤位于导管内乳头状粘液性腺瘤(IPMA)内。在IPMA病变中,偶见幽门型腺体聚集,包括导管衬里细胞在内的大部分细胞表达幽门腺型粘蛋白。本病例的幽门腺化生或分化较常见的幽门腺化生或分化更为广泛。我们认为幽门腺型管状腺瘤是幽门腺化生的IPMA细胞选择性生长所致。
Abstract. We report a rare case of pyloric gland-type tubular adenoma of the main pancreatic duct. It was a grossly visible polypoid nodule and was composed of closely packed pyloric-type glands. This adenoma was present within an intraductal papillary mucinous adenoma (IPMA). In this IPMA lesion, aggregations of pyloric-type glands were occasionally observed, and most of the cells including ductal lining cells expressed pyloric gland-type mucin. The IPMA of the present case showed more extensive pyloric gland metaplasia or differentiation than commonly noted in IPMAs. We consider this pyloric gland-type tubular adenoma to be derived from a selective growth of IPMA cells showing pyloric gland metaplasia.