3D ultrasound guided navigation system with hybrid image fusion.

3D ultrasound guided navigation system with hybrid image fusion.
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DOI:
10.1038/s41598-021-86848-1
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发表时间:
2021-04-23
期刊:
影响因子:
4.6
通讯作者:
Hummel J
Hummel J
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Iommi D;Valladares A;Figl M;Grahovac M;Fichtinger G;Hummel J

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提出了一种融合两种图像模态的导航系统的原型。标准的模态间配准被替换为校准成像设备的基于跟踪器的图像配准。术中经直肠超声(TRUS)图像与术前磁共振(MR)图像合并,用于前列腺活检。MR和TRUS图像之间的配准由额外的腹部3D-US(ab-3D-US)执行,这使得能够通过模态内ab-3D-US/3D-TRUS配准来替换模态间MR/TRUS配准。使用光学跟踪系统(OTS)进行ab-3D-US与MR的术前图像融合的校准程序。使用多锥体体模评估多模态ab-3D-US/MR图像融合的靶配准误差(TRE),使用前列腺体模评估Dice评分和病变的Hausdorff距离。最后,将术前ab- 3D-US与TRUS图像配准,并确定从MR到TRUS转换的误差。ab-3D-US/MR图像配准的TRE为1.81 mm。ab-3D-US和MR的Dice评分和Hausdorff距离分别为0.67和3.19 mm。TRUS和MR的Dice评分和Hausdorff距离分别为0.67和3.18 mm。混合导航系统显示了使用前列腺体模进行融合引导活检手术的足够准确性。该系统可为大多数超声引导活检和消融介入提供术中融合。
A prototype of a navigation system to fuse two image modalities is presented. The standard inter-modality registration is replaced with a tracker-based image registration of calibrated imaging devices. Intra-procedure transrectal US (TRUS) images were merged with pre-procedure magnetic resonance (MR) images for prostate biopsy. The registration between MR and TRUS images was performed by an additional abdominal 3D-US (ab-3D-US), which enables replacing the inter-modal MR/TRUS registration by an intra-modal ab-3D-US/3D-TRUS registration. Calibration procedures were carried out using an optical tracking system (OTS) for the pre-procedure image fusion of the ab-3D-US with the MR. Inter-modal ab-3D-US/MR image fusion was evaluated using a multi-cone phantom for the target registration error (TRE) and a prostate phantom for the Dice score and the Hausdorff distance of lesions . Finally, the pre-procedure ab- 3D-US was registered with the TRUS images and the errors for the transformation from the MR to the TRUS were determined. The TRE of the ab-3D-US/MR image registration was 1.81 mm. The Dice-score and the Hausdorff distance for ab-3D-US and MR were found to be 0.67 and 3.19 mm. The Dice score and the Hausdorff distance for TRUS and MR were 0.67 and 3.18 mm. The hybrid navigation system showed sufficient accuracy for fusion guided biopsy procedures with prostate phantoms. The system might provide intra-procedure fusion for most US-guided biopsy and ablation interventions.
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