ARSENIC LEVELS IN FINGERNAILS AS A BIOLOGICAL INDICATOR OF EXPOSURE TO ARSENIC
ARSENIC LEVELS IN FINGERNAILS AS A BIOLOGICAL INDICATOR OF EXPOSURE TO ARSENIC
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DOI：
10.1080/15298669091370293
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发表时间：
1990-12-01
期刊：
影响因子：
--
通讯作者：
JOHNS, RE
中科院分区：
文献类型：
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作者：
AGAHIAN, B;LEE, JS;JOHNS, RE
尿液、血液和头发的分析以前曾用于监测职业性砷暴露。虽然砷通常存在于人类指甲中（通常是由于饮食因素），但本研究评估了指甲中砷水平作为职业性接触该元素的生物指标的潜在用途。空气样本和指甲剪下的个人没有接触和高，中，低接触。一个洗涤技术，以前开发的去除外源性砷的头发，修改为洗指甲样本收集在这项研究中。结果表明，98%的外源性砷从这些指甲中被去除。在每个暴露组的平均空气砷浓度与指甲中相应的砷水平的比较中观察到了较高的相关系数（r=0.89）。从收集的数据中，推导出一个方程，由指甲中的砷含量估计工人的空气砷暴露水平;空气砷浓度（μ g As/m3）= 1.79 × 104。指甲砷水平（μ gAs/g指甲）-5.9。
The analysis of urine, blood, and hair has been used previously to monitor occupational exposure to arsenic (As). Although arsenic is normally present in human fingernails (usually as a result of dietary factors), this study evaluated the potential use of levels of arsenic in fingernails as a biological indicator of occupational exposue to this element. Air samples and fingernail clippings were obtained from individuals with no exposure and high, medium, and low exposure. A washing technique, previously developed to remove exogenous arsenic from hair, was modified to wash the fingernail samples collected in this study. It was demonstrated that 98% of exogenous arsenic was removed from these nails. A high correlation coefficient (r=0.89) was observed in a comparison of the mean air arsenic concentrations of each exposure group with corresponding aresenic levels in fingernails. From the data collected, an equation was derived to estimate the air arsenic exposure level for a worker from the arsenic content of fingernails; air arsenic concentration (.mu.g As/m3) = 1.79 .times. fingernail arsenic level (.mu.g As/g nail) - 5.9.