Transient News Events Test: Feasibility in assessment of post-temporal lobectomy remote memory deficits
Transient News Events Test: Feasibility in assessment of post-temporal lobectomy remote memory deficits
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DOI：
10.1016/j.yebeh.2009.06.012
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发表时间：
2009-09-01
影响因子：
2.6
通讯作者：
O'Connor, Margaret G.
中科院分区：
文献类型：
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作者：
Leeman, Beth A.;Macklin, Eric A.;O'Connor, Margaret G.
虽然癫痫患者的顺行性记忆缺陷被很好地记录下来，但远距离记忆缺陷发生的程度还不太清楚。这部分是由于缺乏可靠的评估方法。本研究探讨了使用暂时性新闻事件测试(TNET)评估受试者在前颞叶切除术(ATL)治疗难治性癫痫后远程记忆的可行性。结果表明，与健康对照组相比，患者组的表现明显较差。在患者组中，只有最近时间段的项目表现出明显的下降。对ATL最遥远记忆的稳定性的原因和对海马区功能的影响进行了综述。总之，TNET为评估癫痫患者的远程记忆功能提供了一种可行的方法，在这项回顾性研究中，与健康对照组相比，TNET的表现有所下降。(C)2009 Elsevier Inc.保留所有权利。
Although anterograde memory deficits are well documented in patients with epilepsy, the extent to which remote memory deficits occur is less clear. This is due in part to a lack of reliable methods for assessment. The present study examined the feasibility of using the Transient News Events Test (TNET) to assess remote memory in subjects status post anterior temporal lobectomy (ATL) for the treatment of refractory seizures. Results indicated significantly poorer performance of the patient group compared to healthy controls. The decrement in performance within the patient group was evident only for items from more recent time periods. Reasons for an apparent stability of the most remote memories with ATL and implications regarding hippocampal function are reviewed. In conclusion, the TNET provides a feasible method for assessment of remote memory function in patients with epilepsy, with decrements in performance noted in comparison to a healthy control group in this retrospective study. (c) 2009 Elsevier Inc. All rights reserved.