The interrelationship of malnutrition and diarrhea in a periurban area outside Alexandria, Egypt.
The interrelationship of malnutrition and diarrhea in a periurban area outside Alexandria, Egypt.
复制标题
埃及亚历山大郊外城郊地区营养不良和腹泻的相互关系。
DOI：
10.1097/00005176-200102000-00018
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发表时间：
2001
影响因子：
2.9
通讯作者：
Clemens,JD
中科院分区：
文献类型：
--
作者：
Wierzba,TF;El-Yazeed,RA;Savarino,SJ;Mourad,AS;Rao,M;Baddour,M;El-Deen,AN;Naficy,AB;Clemens,JD
背景在发展中国家，经常观察到儿童同时患有腹泻和营养不良。这一观察结果使许多研究人员推测，腹泻可能导致营养不良，而营养不良可能导致腹泻。在这项研究中，腹泻和营养不良之间的相互关系进行了调查，在143埃及儿童不到3 years age.MethodsFor 22个月，儿童腹泻每周两次家访，并在大约3个月的间隔测量营养状况。营养测量转换为Z-分数的基础上，国家卫生统计中心/世界卫生组织（NCHS/WHO）referencepustry. ResultsThirty 58 hemorrhoeal事件报道，只有1%的事件持续14天或以上。在这些儿童中，分别有19%、3%和7%的儿童发育迟缓、消瘦和年龄别体重偏低。当测试营养不良是否易患腹泻时，年龄别体重z评分<-2标准差与腹泻发病率增加相关（RR= 1.7，P< 0.01），但与年龄别身高或身高别体重无关。腹泻本身与随后的腹泻发作相关（RR= 2.1，P< 0.001）。在短期随访（约3个月）期间，检测到腹泻发作与年龄别身高z评分（-0.16，P< 0.05）的生长迟缓之间存在关联。这种关联被减少，但是，在6个月的时间间隔进行分析时，如果没有腹泻，在任何第一或第二半的这个interval.ConclusionsIn中度营养不良的人群，低体重的年龄和腹泻本身与腹泻风险增加。当儿童有足够的时间进行追赶性生长时，腹泻本身似乎并不会对营养不良产生重大影响。
BackgroundIn the developing world, children are often observed to have both diarrhea and malnutrition. This observation has led many researchers to speculate that diarrhea may produce malnutrition and that malnutrition may predispose to diarrhea. In this study, the interrelationship between diarrhea and malnutrition was investigated among 143 Egyptian children less than 3 years of age.MethodsFor 22 months, children were followed for diarrhea at twice weekly home visits and measured for nutritional status at approximately 3-month intervals. Nutritional measurements were converted to z-scores based on the National Center for Health Statistics/World Health Organization (NCHS/WHO) reference population.ResultsThree hundred fifty-eight diarrheal episodes were reported with only 1% of episodes lasting 14 days or more. Stunting, wasting, and low weight-for-age were found in 19%, 3%, and 7%, of these children, respectively. When testing whether malnutrition predisposes to diarrhea, a weight-for-age z-score of<− 2 standard deviations was associated with increased incidence of diarrhea (RR= 1.7, P< 0.01) but not height-for-age or weight-for-height. Diarrhea itself was associated with a subsequent attack of diarrhea (RR= 2.1, P< 0.001). During short intervals of follow-up (approximately 3 months), an association was detected between diarrhea episodes and growth faltering for height-for-age z-score (− 0.16, P< 0.05). This association was reduced, however, when analyzed during 6-month intervals, if no diarrhea was reported in either the first or second half of this interval.ConclusionsIn a population with moderate malnutrition, both low weight-for-age and diarrhea itself are associated with increased diarrhea risk. Diarrhea alone does not appear to contribute substantially to malnutrition when children have diarrhea-free time for catch-up growth.