Physical activity and mortality in men and women with diagnosed cardiovascular disease
Physical activity and mortality in men and women with diagnosed cardiovascular disease
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DOI：
10.1097/hjr.0b013e32831f1b77
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发表时间：
2009-04-01
影响因子：
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通讯作者：
Stamatakis, Emmanuel
中科院分区：
文献类型：
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作者：
Hamer, Mark;Stamatakis, Emmanuel
背景 关于二级预防的最佳体力活动类型和量的现有信息存在争议。我们研究了不同类型的体力活动（家庭活动、步行、运动）与患有心血管疾病 (CVD) 的参与者的死亡率之间的关联。方法数据收集自苏格兰健康调查（1995 年、1998 年、2003 年），该调查与基于患者的 CVD 入院和死亡数据库相关联。基线时有 837 名男性和女性患有临床确诊的 CVD，其中 175 人在平均 5.6 +/- 3.1 年的随访期间死亡。 结果 全因死亡率风险最低的参与者每周至少进行 20 分钟的体育活动（完全调整的风险比 = 0.32，95% 置信区间 = 0.16-0.65）或步行（风险比 = 0.74， 0.53-1.04）。 CVD 死亡率也观察到类似的关联。体育锻炼者还表现出较低水平的炎症风险标志物和较高的高密度脂蛋白胆固醇。 结论 患有 CVD 的男性和女性每周至少参加 20 分钟的中度至剧烈活动，显示出全因死亡和心血管死亡的风险最低。这些发现支持了受控运动训练研究的新数据。 Eur J Cardiovasc Prev Rehabil 16:156-160 (C) 2009 欧洲心脏病学会
Background Existing information regarding the optimal types and amount of physical activity for secondary prevention is controversial. We examined the association between different types of physical activity (domestic, walking, sports) and mortality in participants with established cardiovascular disease (CVD).Methods Data were collected from the Scottish Health Surveys (1995, 1998, 2003) that were linked to a patient-based database of CVD hospital admissions and deaths. There were 837 men and women with clinically confirmed CVD at baseline, of whom 175 died over an average of 5.6 +/- 3.1 years of follow-up.Results The lowest risks for all-cause mortality were seen in participants undertaking at least 20 min/week of sports activity (fully adjusted hazard ratio=0.32, 95% confidence interval=0.16-0.65) or walking (hazard ratio=0.74, 0.53-1.04). Similar associations were observed for CVD mortality. The physically active also showed lower levels of inflammatory risk markers and greater HDL cholesterol.Conclusion Men and women with existing CVD who participate in moderate-to-vigorous activity for at least 20 min/week showed the lowest risks of all-cause and cardiovascular mortality. These findings support emerging data from controlled exercise training studies. Eur J Cardiovasc Prev Rehabil 16:156-160 (C) 2009 The European Society of Cardiology