The effects of naltrexone on alcohol and cocaine use in dually addicted patients
The effects of naltrexone on alcohol and cocaine use in dually addicted patients
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DOI:
10.1016/s0740-5472(98)00039-7
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发表时间:
1999-03-01
影响因子:
3.9
通讯作者:
O'Brien, CP
中科院分区:
文献类型:
--
作者:
Oslin, DW;Pettinati, HM;O'Brien, CP
Concurrent dependence on cocaine and alcohol is common among patients seeking addiction treatment. This study was undertaken to explore the effectiveness of naltrexone (150 mg) as a potential treatment for patients who are alcohol and cocaine dependent. Of 15 subjects enrolled in the 12-week, open medication trial, 7 subjects did riot complete the study. Relapse to clinically significant drinking occurred in 7 subjects (47%). There was a reduction in the average daily amount of alcohol consumed from pretreatment to treatment (p