Moving Toward a Precision-Based, Personalized Framework for Prevention Science: Introduction to the Special Issue
Moving Toward a Precision-Based, Personalized Framework for Prevention Science: Introduction to the Special Issue
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DOI：
10.1007/s11121-018-0955-9
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发表时间：
2019-01-01
影响因子：
3.5
通讯作者：
Gewirtz, Abigail
中科院分区：
文献类型：
--
作者：
August, Gerald J.;Gewirtz, Abigail
本期特刊的目的是向预防科学家介绍一种新兴的医疗保健形式，即精准医学。这种方法将疾病和危害健康行为的机制研究与个人层面的预防、治疗和治愈结合起来。精准医学及其衍生的个性化预防代表了预防科学的一个有前途的范例，因为它解释了反应的异质性，并指导有针对性的干预措施的发展，这可能会提高项目的效果。如果成功地整合到预防科学研究中，个性化预防是一种方法，可以为决策支持工具（筛查措施、规定性算法）的开发提供信息，并增强移动卫生技术的效用，使从业人员能够使用个性化消费者数据，为特定个人或个人亚群体的最佳预防策略类型和/或强度的决策提供信息。在这期特刊中，我们提出了一些概念性文章，为基于精确的个性化预防研究和实证研究提供了一个启发式框架，这些研究解决了新一代基于精确的个性化预防干预的研究问题，重点是儿童心理健康、行为健康和教育。
The goal of this Special Issue is to introduce prevention scientists to an emerging form of healthcare, called precision medicine. This approach integrates investigation of the mechanisms of disease and health-compromising behaviors with prevention, treatment, and cure resolved at the level of the individual. Precision Medicine and its derivative personalized prevention represents a promising paradigm for prevention science as it accounts for response heterogeneity and guides development of targeted interventions that may enhance program effect sizes. If successfully integrated into prevention science research, personalized prevention is an approach that can inform the development of decision support tools (screening measures, prescriptive algorithms) and enhance the utility of mobile health technologies that will enable practitioners to use personalized consumer data to inform decisions about the best type and/or intensity of a prevention strategy for particular individuals or subgroups of individuals. In this special issue, we present conceptual articles that provide a heuristic framework for precision-based, personalization prevention research and empirical studies that address research questions exemplary of a new generation of precision-based personalized preventive interventions focused on children's mental health, behavioral health, and education.