Multicompartment Block Polymer Micelles
Multicompartment Block Polymer Micelles
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DOI：
10.1021/ma201865s
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发表时间：
2012-01-10
期刊：
影响因子：
5.5
通讯作者：
Lodge, Timothy P.
中科院分区：
文献类型：
--
作者：
Moughton, Adam O.;Hillmyer, Marc A.;Lodge, Timothy P.
多隔室胶束是一类有趣的自组装聚集体，具有细分的疏溶剂核。它们已经受到广泛的研究，部分原因是由于它们独特的形态和螯合特性，这是由于多个不同的化学环境在一个纳米结构内非常接近。多隔室胶束具有用于各种应用的潜力，包括多种不相容药物有效载荷的治疗递送。本观点回顾了最近的成就，在战略的合成，自组装和形态控制的多室胶束和突出未来的挑战和潜在的应用。
Multicompartment micelles are an intriguing class of self-assembled aggregates with subdivided solvophobic cores. They have been subject to extensive research in part due to their unique morphological and sequestration properties as a result of multiple distinct chemical environments being in close proximity within one nanostructure. Multicompartment micelles hold potential for use in various applications that include the therapeutic delivery of multiple incompatible drug payloads. The present Perspective reviews recent achievements in strategies for the synthesis, self-assembly, and morphological control of multicompartment-micelles and highlights future challenges and potential applications.