Identification of IgA binding structures in skin of patients with dermatitis herpetiformis.
Identification of IgA binding structures in skin of patients with dermatitis herpetiformis.
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疱疹样皮炎患者皮肤中 IgA 结合结构的鉴定。
DOI：
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发表时间：
1978
影响因子：
6.5
通讯作者：
H. Yaoita
中科院分区：
文献类型：
--
作者：
H. Yaoita
免疫电镜和超微结构鉴定的结构，结合伊加在疱疹样皮炎（DH）患者的皮肤揭示了他们是，在一定程度上，一个复杂的纤维成分覆盖着无定形物质。其中一根纤维直径为80- 130埃，呈管状，类似于真皮微纤维束或弹性纤维的微管元件。这些结构有时与真皮微纤维束相关，并在靠近真皮-表皮交界处的弹性纤维系统内发现。两者合计，这些研究结果表明，结合伊加的结构是独特的DH，可能是一个异常的真皮微原纤维弹力纤维系统的一部分。
Immunoelectronmicroscopic and ultrastructural identification of the structures which bind IgA in skin of patients with dermatitis herpetiformis (DH) reveals them to be, in part, a complex of fibrillar components which are covered with amorphous substances. One of the fibers has a diameter of 80--130 A and appears to be tubular, resembling dermal microfibrillar bundles or microtubular elements of elastic fibers. The structures, at times, are associated with the dermal microfibrillar bundles and are found within an elastic fiber system which is in close proximity to the dermal-epidermal junction. Taken together, these findings suggest that the structures which bind IgA are unique to DH and might be a part of an abnormal dermal microfibrillar bundle-elastic fiber system.