Subgingival microflora and periodontitis.
Subgingival microflora and periodontitis.
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龈下微生物区系和牙周炎。
DOI：
10.1111/j.1600-0765.1976.tb00045.x
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发表时间：
1976
影响因子：
3.5
通讯作者：
J. Sherris
中科院分区：
文献类型：
--
作者：
B. Williams;R. M. Pantalone;J. Sherris
对龈下菌斑中的主要细菌菌群进行了表征，并根据牙周病的病因进行了评估。研究人员对一小组临床和放射学鉴定的牙周患者和对照受试者进行了研究。对可栽培植物群进行了全面的清查。最常见的生物群是革兰氏阳性杆菌，其中大多数是放线菌。分离出的厌氧革兰氏阴性杆菌的比例比先前研究结果中显示的比例更大。在同一患者的不同部位发现花含量存在相当大的差异。然而，同一患者的临床正常部位和病理部位之间的菌群没有观察到统计学上的显着差异。与对照受试者相比，牙周患者菌群中存在显着更多数量的兼性放线菌。
通过间接免疫荧光法检测了来自同一 9 名受试者的血清中针对 12 种菌斑细菌的循环抗体。牙周患者和对照受试者的血清之间没有观察到抗体滴度存在差异。
Predominant bacterial flora resident in subgingival plaque was characterized and evaluated in relation to the etiology of periodontal disease. Small groups of clinically and radiographically identified periodontal patients and control subjects were studied. A comprehensive inventory of cultivable flora was made. The most common group of organisms were the Gram-positive rods, the majority of which were Actinomyces. A larger proportion of anaerobic Gram-negative rods were isolated than indicated in the results of previous studies. Considerable variability in floral content was found in different sites in the same patient. However, no statistically significant differences were observed in the flora between clinically normal and pathological sites of the same patients. A significantly greater number of facultative Actinomyces was present in the flora of periodontal patients as compared to control subjects.
Sera from the same nine subjects were assayed by indirect immunofluorescence for circulating antibodies to 12 strains of plaque bacteria. No differences in antibody titers were observed between sera from periodontal patients and control subjects.